دورية أكاديمية
Dietary organic acids ameliorate high stocking density stress-induced intestinal inflammation through the restoration of intestinal microbiota in broilers
العنوان: | Dietary organic acids ameliorate high stocking density stress-induced intestinal inflammation through the restoration of intestinal microbiota in broilers |
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المؤلفون: | Dong Dai, Guanghai Qi, Jing Wang, Haijun Zhang, Kai Qiu, Yanming Han, Yuanyuan Wu, Shugeng Wu |
المصدر: | Journal of Animal Science and Biotechnology, Vol 13, Iss 1, Pp 1-15 (2022) |
بيانات النشر: | BMC, 2022. |
سنة النشر: | 2022 |
المجموعة: | LCC:Animal culture LCC:Veterinary medicine |
مصطلحات موضوعية: | Broiler, High stocking density, Intestinal inflammation, Intestinal microbiota, Organic acid, Short-chain fatty acid, Animal culture, SF1-1100, Veterinary medicine, SF600-1100 |
الوصف: | Abstract Background High stocking density (HSD) stress has detrimental effects on growth performance, intestinal barrier function, and intestinal microbiota in intensive animal production. Organic acids (OA) are widely used as feed additives for their ability to improve growth performance and intestinal health in poultry. However, whether dietary OA can ameliorate HSD stress-induced impaired intestinal barrier in broilers remains elusive. In this study, a total of 528 one-day-old male Arbor Acres broilers were randomly allocated into 3 treatments with 12 replicates per treatment including 10 birds for normal stocking density and 17 birds for HSD. The dietary treatments were as follows: 1) Normal stocking density + basal diet; 2) HSD + basal diets; 3) HSD + OA. Results HSD stress can induce increased levels of serum corticosterone, lipopolysaccharides, interleukin-1β, tumor necrosis factor-α, and down-regulated mRNA expression of ZO-1, resulting in compromised growth performance of broilers (P |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2049-1891 |
Relation: | https://doaj.org/toc/2049-1891 |
DOI: | 10.1186/s40104-022-00776-2 |
URL الوصول: | https://doaj.org/article/e44427723b144df59dfc0e713b2cd85b |
رقم الأكسشن: | edsdoj.44427723b144df59dfc0e713b2cd85b |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 20491891 |
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DOI: | 10.1186/s40104-022-00776-2 |