دورية أكاديمية
Obesity and adiposity of 3- to 6-year-old children born to mothers with hyperglycaemia first detected in pregnancy in an urban South African setting
| العنوان: | Obesity and adiposity of 3- to 6-year-old children born to mothers with hyperglycaemia first detected in pregnancy in an urban South African setting |
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| المؤلفون: | Larske M. Soepnel, Veronique Nicolaou, Christine Slater, Glory Chidumwa, Naomi S. Levitt, Kerstin Klipstein-Grobusch, Shane A. Norris |
| المصدر: | Annals of Human Biology, Vol 48, Iss 2, Pp 81-92 (2021) |
| بيانات النشر: | Taylor & Francis Group, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Biology (General) LCC:Human anatomy LCC:Physiology |
| مصطلحات موضوعية: | gestational hyperglycaemia, childhood obesity, childhood adiposity, south africa, maternal bmi, Biology (General), QH301-705.5, Human anatomy, QM1-695, Physiology, QP1-981 |
| الوصف: | Background Understanding the association between maternal metabolic conditions in pregnancy and the risk of childhood overweight, a growing concern in sub-Saharan Africa (SSA), helps to identify opportunities for childhood obesity prevention. Aim To assess the association between hyperglycaemia first detected in pregnancy (HFDP) (gestational diabetes mellitus [GDM] and diabetes in pregnancy [DIP]) and child obesity and adiposity in pre-school-aged children in South Africa, independently of maternal BMI. Subjects and methods Measurement of anthropometry and fat mass index (FMI) by the deuterium dilution method was done for 102 3–6-year-old children born to mothers with HFDP and 102 HFDP-unexposed children. Hierarchical regression analysis and generalised structural equation modelling (GSEM) were performed. Results The prevalence of overweight/obesity was 10.5% and 11.1% in children exposed to GDM and DIP, respectively, and 3.9% in the HFDP-unexposed group. Log-transformed FMI was significantly higher in the DIP-exposed group (β = 0.166, 95% CI = 0.014–0.217 p= .026), but not when adjusting for maternal pregnancy BMI (β = 0.226, 95% CI = 0.003–0.015, p = .004). GSEM showed significant total effects of maternal BMI and birth weight on FMI/BMI. Conclusions Maternal pregnancy BMI seems to play a greater role in the development of childhood adiposity than maternal hyperglycaemia, requiring further research and identifying maternal BMI as a relevant prevention target in our setting. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0301-4460 1464-5033 03014460 |
| Relation: | https://doaj.org/toc/0301-4460; https://doaj.org/toc/1464-5033 |
| DOI: | 10.1080/03014460.2021.1918245 |
| URL الوصول: | https://doaj.org/article/c4475f413e4f42e69eb6dd5b9d0623f7 |
| رقم الأكسشن: | edsdoj.4475f413e4f42e69eb6dd5b9d0623f7 |
| قاعدة البيانات: | Directory of Open Access Journals |
PDF full text from Publisher | تدمد: | 03014460 14645033 |
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| DOI: | 10.1080/03014460.2021.1918245 |