دورية أكاديمية
Acrokeratosis Paraneoplastica Associated with Cervical Squamous Cell Carcinoma
| العنوان: | Acrokeratosis Paraneoplastica Associated with Cervical Squamous Cell Carcinoma |
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| المؤلفون: | Bryan Squires, Steven D. Daveluy, Michael C. Joiner, Newton Hurst, Michael Bishop, Steven R. Miller |
| المصدر: | Case Reports in Dermatological Medicine, Vol 2016 (2016) |
| بيانات النشر: | Hindawi Limited, 2016. |
| سنة النشر: | 2016 |
| المجموعة: | LCC:Dermatology |
| مصطلحات موضوعية: | Dermatology, RL1-803 |
| الوصف: | Background. Acrokeratosis paraneoplastica, or Bazex syndrome, is a paraneoplastic syndrome characterized by cutaneous psoriasiform lesions with associated acral erythema and scale, as well as nail changes, including onycholysis and ungual dystrophy. Its most advanced, severe form involves the trunk, elbows, and knees. It is typically associated with upper aerodigestive tract malignancies in males. Rare cases associated with gynecological cancers have been reported, including uterine adenocarcinoma, as well as ovarian and vulvar squamous cell carcinomas. Cutaneous manifestations often precede cancer diagnosis. In most reported cases, skin changes resolve when the underlying malignancy is adequately treated. Main Observations. We present the case of a 56-year-old female diagnosed with acrokeratosis paraneoplastica following the discovery of FIGO stage IIB cervical squamous cell carcinoma (SCC). Scaling, hyperpigmentation, xerosis, and fissuring were noted on the patient’s hands, feet, legs, arms, and lower back. Pitting was noted on her fingernails. Her cervical cancer was successfully treated with chemoradiotherapy, after which her cutaneous lesions persisted for two months before resolving. Conclusions. The presentation of acrokeratosis paraneoplastica in this context is atypical. Reports of associations with gynecological cancers, as in our patient’s case, are exceedingly rare. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2090-6463 2090-6471 |
| Relation: | https://doaj.org/toc/2090-6463; https://doaj.org/toc/2090-6471 |
| DOI: | 10.1155/2016/7137691 |
| URL الوصول: | https://doaj.org/article/44ad1445cd674f2cbe332670ec5de2dd |
| رقم الأكسشن: | edsdoj.44ad1445cd674f2cbe332670ec5de2dd |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20906463 20906471 |
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| DOI: | 10.1155/2016/7137691 |