Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen

التفاصيل البيبلوغرافية
العنوان:	Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen
المؤلفون:	Celia Miguel-Blanco, Irene Molina, Ana I. Bardera, Beatriz Díaz, Laura de las Heras, Sonia Lozano, Carolina González, Janneth Rodrigues, Michael J. Delves, Andrea Ruecker, Gonzalo Colmenarejo, Sara Viera, María S. Martínez-Martínez, Esther Fernández, Jake Baum, Robert E. Sinden, Esperanza Herreros
المصدر:	Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
بيانات النشر:	Nature Portfolio, 2017.
سنة النشر:	2017
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	There is a need forPlasmodium transmission blocking drugs for malaria elimination. Here, Miguel-Blanco et al. screen >10,000 compounds against stage V female gametocytes, identify active compounds belonging to 57 chemotypes and confirm transmission blocking activity of four selected compounds in vitro.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
Relation:	https://doaj.org/toc/2041-1723
DOI:	10.1038/ncomms15160
URL الوصول:	https://doaj.org/article/ca4505d3d02c492988049e0313f6978a
رقم الأكسشن:	edsdoj.4505d3d02c492988049e0313f6978a
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/ncomms15160