دورية أكاديمية
Effect of Physiological Fluid on the Photothermal Properties of Gold Nanostructured
العنوان: | Effect of Physiological Fluid on the Photothermal Properties of Gold Nanostructured |
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المؤلفون: | María Fernanda Amézaga González, Jazzely Acosta Bezada, Víctor Gómez Flores, Christian Chapa González, Jose Rurik Farias Mancilla, S. J. Castillo, Carlos Avila Orta, Perla E. García-Casillas |
المصدر: | International Journal of Molecular Sciences, Vol 24, Iss 9, p 8339 (2023) |
بيانات النشر: | MDPI AG, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Biology (General) LCC:Chemistry |
مصطلحات موضوعية: | gold nanoparticles, photothermal properties, light-to-heat efficiency, Biology (General), QH301-705.5, Chemistry, QD1-999 |
الوصف: | Colloidal gold particles have been extensively studied for their potential in hyperthermia treatment due to their ability to become excited in the presence of an external laser. However, their light-to-heat efficiency is affected by the physiologic environment. In this study, we aimed to evaluate the ability of gold sphere, rod, and star-shaped colloids to elevate the temperature of blood plasma and breast cancer-simulated fluid under laser stimulation. Additionally, the dependence of optical properties and colloid stability of gold nanostructures with physiological medium, particle shape, and coating was determined. The light-to-heat efficiency of the gold particle is shape-dependent. The light-to-heat conversion efficiency of a star-shaped colloid is 36% higher than that of sphere-shaped colloids. However, the raised temperature of the surrounding medium is the lowest in the star-shaped colloid. When gold nanostructures are exited with a laser stimulation in a physiological fluid, the ions/cations attach to the surface of the gold particles, resulting in colloidal instability, which limits electron oscillation and diminishes the energy generated by the plasmonic excitation. Fluorescein (Fl) and polyethylene glycol (PEG) attached to gold spheres enhances their colloidal stability and light-to-heat efficiency; post-treatment, they remand their optical properties. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1422-0067 1661-6596 |
Relation: | https://www.mdpi.com/1422-0067/24/9/8339; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067 |
DOI: | 10.3390/ijms24098339 |
URL الوصول: | https://doaj.org/article/4560a6fc6d484fd8b9f8a75c7cedc6cb |
رقم الأكسشن: | edsdoj.4560a6fc6d484fd8b9f8a75c7cedc6cb |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 14220067 16616596 |
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DOI: | 10.3390/ijms24098339 |