دورية أكاديمية
Hidden diagnosis of multiple endocrine neoplasia-1 unraveled during workup of virilization caused by adrenocortical carcinoma
| العنوان: | Hidden diagnosis of multiple endocrine neoplasia-1 unraveled during workup of virilization caused by adrenocortical carcinoma |
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| المؤلفون: | Sandeep Kharb, Aditi Pandit, Abhay Gundgurthi, M K Garg, K S Brar, N Kannan, Reena Bharwaj |
| المصدر: | Indian Journal of Endocrinology and Metabolism, Vol 17, Iss 3, Pp 514-518 (2013) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2013. |
| سنة النشر: | 2013 |
| المجموعة: | LCC:Diseases of the endocrine glands. Clinical endocrinology LCC:Diseases of the digestive system. Gastroenterology |
| مصطلحات موضوعية: | Adrenocortical carcinoma, Cushing′s syndrome, multiple endocrine neoplasia-1, virilizing syndrome, Diseases of the endocrine glands. Clinical endocrinology, RC648-665, Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: | Multiple endocrine neoplasia-1 (MEN1) is an autosomal dominant syndrome with classic triad of parathyroid hyperplasia, pancreatic neuroendocrine tumors, and pituitary adenomas. Other recognized manifestations include carcinoid, cutaneous or adrenocortical tumors. It is commonly presented with clinical features related to parathyroid, pancreas or pituitary lesions. Here, we have presented a case that had virilization and biochemical Cushing′s syndrome due to adrenocortical carcinoma as presenting feature of MEN1. Cushing′s syndrome in MEN1 is an extremely rare and usually late manifestation and most cases are due to corticotropin-producing pituitary adenomas. Although Cushing′s syndrome generally develops years after the more typical manifestations of MEN1 appear, it may be the primary manifestation of MEN1 syndrome particularly when related to adrenal adenoma or carcinoma. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2230-8210 2230-9500 |
| Relation: | http://www.ijem.in/article.asp?issn=2230-8210;year=2013;volume=17;issue=3;spage=514;epage=518;aulast=Kharb; https://doaj.org/toc/2230-8210; https://doaj.org/toc/2230-9500 |
| DOI: | 10.4103/2230-8210.111672 |
| URL الوصول: | https://doaj.org/article/45e637d25caf4d45ae6ee4bbb0b991ed |
| رقم الأكسشن: | edsdoj.45e637d25caf4d45ae6ee4bbb0b991ed |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22308210 22309500 |
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| DOI: | 10.4103/2230-8210.111672 |