دورية أكاديمية
أعرض في EDS

Mechanical Stretch Induced Skin Regeneration: Molecular and Cellular Mechanism in Skin Soft Tissue Expansion

التفاصيل البيبلوغرافية
العنوان: Mechanical Stretch Induced Skin Regeneration: Molecular and Cellular Mechanism in Skin Soft Tissue Expansion
المؤلفون: Yaotao Guo, Yajuan Song, Shaoheng Xiong, Tong Wang, Wei Liu, Zhou Yu, Xianjie Ma
المصدر: International Journal of Molecular Sciences, Vol 23, Iss 17, p 9622 (2022)
بيانات النشر: MDPI AG, 2022.
سنة النشر: 2022
المجموعة: LCC:Biology (General)
LCC:Chemistry
مصطلحات موضوعية: skin soft tissue expansion, mechanical stretch, signaling pathway, cell adhesion molecules, transcriptome sequencing, skin stem cell, Biology (General), QH301-705.5, Chemistry, QD1-999
الوصف: Skin soft tissue expansion is one of the most basic and commonly used techniques in plastic surgery to obtain excess skin for a variety of medical uses. However, skin soft tissue expansion is faced with many problems, such as long treatment process, poor skin quality, high retraction rate, and complications. Therefore, a deeper understanding of the mechanisms of skin soft tissue expansion is needed. The key to skin soft tissue expansion lies in the mechanical stretch applied to the skin by an inflatable expander. Mechanical stimulation activates multiple signaling pathways through cellular adhesion molecules and regulates gene expression profiles in cells. Meanwhile, various types of cells contribute to skin expansion, including keratinocytes, dermal fibroblasts, and mesenchymal stem cells, which are also regulated by mechanical stretch. This article reviews the molecular and cellular mechanisms of skin regeneration induced by mechanical stretch during skin soft tissue expansion.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1422-0067
1661-6596
Relation: https://www.mdpi.com/1422-0067/23/17/9622; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067
DOI: 10.3390/ijms23179622
URL الوصول: https://doaj.org/article/45ecc5609e4748c1a3c4d13e59c6a841
رقم الأكسشن: edsdoj.45ecc5609e4748c1a3c4d13e59c6a841
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14220067
16616596
DOI:10.3390/ijms23179622