دورية أكاديمية
Social and psychological survey on paroxysmal kinesigenic dyskinesia patients in China
| العنوان: | Social and psychological survey on paroxysmal kinesigenic dyskinesia patients in China |
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| المؤلفون: | Wo-tu TIAN, Xiao-jun HUANG, Gui-ling LIANG, Chen-xi ZHU, Ying SHEN, Yu FANG, Mu-han CHEN, Jun-yi SHEN, Sheng-di CHEN, Li CAO |
| المصدر: | Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 17, Iss 8, Pp 590-596 (2017) |
| بيانات النشر: | Tianjin Huanhu Hospital, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Neurology. Diseases of the nervous system |
| مصطلحات موضوعية: | Movement disorders, Neuropsychology, Quality of life, Neurology. Diseases of the nervous system, RC346-429 |
| الوصف: | Background Paroxysmal kinesigenic dyskinesia (PKD) is a rare involuntary movement disorder characterized by transient and recurrent dystonic or choreoathetoid attacks triggered by sudden voluntary movements. Since 2011, progress in genetics and pathophysiology has been made. Our study aimed to investigate and analyze the characteristics of social behavior, quality of life and related factors in patients with PKD in China. Methods A cross.sectional study was conducted regarding health.related behaviors in 188 patients with PKD by using the Chinese Version of Symptom Check List-90 (SCL-90) and World Health Organization Quality of Life-100 (WHOQoL -100) questionnaires. Psychometric symptoms, mental health, quality of life and related factors were all investigated and analyzed. Results A total of 120 valid questionnaires were statistically analyzed. Compared with Chinese norm, patients with PKD showed significantly higher scores in global severity index (GSI, P = 0.000) and SCL-90 scores (somatization, obsessive . compulsive, interpersonal sensitivity, depression, anxiety, hostility, phobic anxiety, paranoid ideation, psychoticism; P = 0.000, for all). Patients with PKD also showed significantly lower scores than Chinese norm in general quality of life (P = 0.000) and four domains of WHOQoL -100 (physiological domain, psychological domain, independence domain, social relationship domain; P = 0.000, for all). Pearson and partial correlation analysis showed that quality of life of PKD patients was in positive correaltion with complex PKD and remission (P = 0.016, 0.000), while was in negative correaltion with somatization, obsessive.compulsive, interpersonal sensitivity, depression, anxiety, hostility, phobic anxiety, paranoid ideation and psychoticism (P = 0.000, for all). The results of multiple linear regresssion analysis showed that lower quality of life was in association with remission (P = 0.024) and depression (P = 0.000). The degree of impact was R2 value 0.423 for remission and R2 value 0.398 for depression. Conclusions The prevalence of psychometric symptoms and poor quality of life in PKD patients were studied and the efforts to recognize and detect comorbid interictal psychological distress were important, especially for the patients with higher depression score and without remission trend. DOI: 10.3969/j.issn.1672-6731.2017.08.007 |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Chinese |
| تدمد: | 1672-6731 |
| Relation: | http://www.cjcnn.org/index.php/cjcnn/article/view/1645; https://doaj.org/toc/1672-6731 |
| URL الوصول: | https://doaj.org/article/da45eee8b6ee418e90f222543e8d70c3 |
| رقم الأكسشن: | edsdoj.45eee8b6ee418e90f222543e8d70c3 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16726731 |
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