دورية أكاديمية
Reproductive toxicity of Carlina gummifera L. incense inhalation in adult male wistar rats
| العنوان: | Reproductive toxicity of Carlina gummifera L. incense inhalation in adult male wistar rats |
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| المؤلفون: | Hallegue Dorsaf, Moujahed Sabrine, Ben Barka Zaineb, Tebourbi Olfa, Sakly Mohsen, Ben Rhouma Khemais |
| المصدر: | Journal of Human Reproductive Sciences, Vol 15, Iss 1, Pp 12-20 (2022) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Gynecology and obstetrics |
| مصطلحات موضوعية: | carlina gummifera l., incense, oxidative stress, reproductive toxicity, sperm, Gynecology and obstetrics, RG1-991 |
| الوصف: | Background: Burning incense of Carlina gummifera L. is a traditional practice in North African countries for religious or ritual intentions. Aim: The aim of this study was to investigate the effects of smoke incense of this plant on the reproductive function in adult male rats. Setting and Design: This study was conducted in the Integrated Physiology Laboratory. Materials and Methods: Plant roots were collected, dried and finely ground in powder form. Adult Wistar rats were randomly assigned to treated groups exposed daily during 60 min for 15 consecutive days to smoke incense at 2, 4 and 6 g and a control group was subjected to the same conditions in the absence of smoke. Statistical Analysis Used: Statistical analysis was performed using one-way analysis of variance followed by Tukey's multiple comparison as the post hoc test. Results: Exposure to the incense of Carlina gummifera L. seriously affected dose dependently the reproductive function in male rats. It was found that in treated groups, the testicle relative weight decreased, while those of seminal vesicles and prostate increased when compared to the untreated group. Carlina gummifera L. incense inhalation reduced the total number, viability and mobility of epididymis spermatozoa compared to control. Furthermore, incense exposure induced various histological changes in the testes, prostate and seminal vesicles, including in particular a decrease in the number of gametes in the seminiferous tubes, the reduction of prostatic secretions and the macrophagic resorption of the seminal secretions. The effect of Carlina incense on the antioxidant system was evaluated by assaying the two antioxidant enzyme activities catalase and superoxide dismutase as well as thiol group levels in the testicles. Our results showed that fumigation affected these parameters, suggesting that the morphological and functional modifications in the male reproductive system induced by Carlina gummifera L. incense may be related, in part, to the alteration of the oxidative balance in the testicle. Conclusion: Smoke incense of Carlina gummifera L. caused marked reproductive toxicity in adult male rats associated with induced oxidative stress. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0974-1208 1998-4766 |
| Relation: | http://www.jhrsonline.org/article.asp?issn=0974-1208;year=2022;volume=15;issue=1;spage=12;epage=20;aulast=Dorsaf; https://doaj.org/toc/0974-1208; https://doaj.org/toc/1998-4766 |
| DOI: | 10.4103/jhrs.jhrs_149_21 |
| URL الوصول: | https://doaj.org/article/460b3d4987584ff2b4e31105148f0b58 |
| رقم الأكسشن: | edsdoj.460b3d4987584ff2b4e31105148f0b58 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 09741208 19984766 |
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| DOI: | 10.4103/jhrs.jhrs_149_21 |