دورية أكاديمية

Cytokine Expression of Lung Bacterial Infection in Newly Diagnosed Adult Hematological Malignancies

التفاصيل البيبلوغرافية
العنوان: Cytokine Expression of Lung Bacterial Infection in Newly Diagnosed Adult Hematological Malignancies
المؤلفون: Zengzheng Li, Zefeng Yang, Peng Hu, Xin Guan, Lihua Zhang, Jinping Zhang, Tonghua Yang, Chaoran Zhang, Renbin Zhao
المصدر: Frontiers in Immunology, Vol 12 (2021)
بيانات النشر: Frontiers Media S.A., 2021.
سنة النشر: 2021
المجموعة: LCC:Immunologic diseases. Allergy
مصطلحات موضوعية: IL-6, IL-8, IL-10, hematological malignancy, lung infection, bacterial, Immunologic diseases. Allergy, RC581-607
الوصف: Adult patients with hematological malignancies are frequently accompanied by bacterial infections in the lungs when they are first diagnosed. Sputum culture, procalcitonin (PCT), C-reactive protein (CRP), body temperature, and other routinely used assays are not always reliable. Cytokines are frequently abnormally produced in adult hematological malignancies associated with a lung infection, it is uncertain if cytokines can predict lung bacterial infections in individuals with hematological malignancies. Therefore, we reviewed 541 adult patients newly diagnosed with hematological malignancies, of which 254 patients had lung bacterial infections and 287 patients had no other clearly diagnosed infections. To explore the predictive value of cytokines for pulmonary bacterial infection in adult patients with hematological malignancies. Our results show that IL-4, IL-6, IL-8, IL-10, IL-12P70, IL-1β, IL-2, IFN-γ, TNF-α, TNF-β and IL-17A are in the lungs The expression level of bacterially infected individuals was higher than that of patients without any infections (P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1664-3224
Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.748585/full; https://doaj.org/toc/1664-3224
DOI: 10.3389/fimmu.2021.748585
URL الوصول: https://doaj.org/article/4671a241c3f1467894a08559b6f2e80d
رقم الأكسشن: edsdoj.4671a241c3f1467894a08559b6f2e80d
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:16643224
DOI:10.3389/fimmu.2021.748585