دورية أكاديمية
Proteasome activity and subunit composition in endometrial hyperplasia and cancer
| العنوان: | Proteasome activity and subunit composition in endometrial hyperplasia and cancer |
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| المؤلفون: | L. V. Spirina, I. V. Kondakova, L. A. Kolomiets, A. L. Chernysova, O. N. Asadchikova, N. P. Sharova, V. D. Koval |
| المصدر: | Опухоли женской репродуктивной системы, Vol 0, Iss 4, Pp 64-67 (2014) |
| بيانات النشر: | ABV-press, 2014. |
| سنة النشر: | 2014 |
| المجموعة: | LCC:Gynecology and obstetrics |
| مصطلحات موضوعية: | рак эндометрия, гиперпластические процессы эндометрия, активность протеасом, субъединичный состав, Gynecology and obstetrics, RG1-991 |
| الوصف: | In endometrial hyperplasia the total proteasome activity was not changed however the 26S proteasome activity was increased in comparison with the normal tissues. In endometrial cancer the high total proteasome activity and activities of 26S and 20S proteasomes wer e revealed. The changes in proteasome activities were correlated with the decreased content of α1α2α3α5α6α7 proteasome subunits and increased con- tents of LMP2, LMP7 and PA28β proteasome subunits compared to that in nonaltered tissues. Low content of α1α2α3α5α6α7 proteasome subunits was revealed at the second stage of cancer patients in comparison with that at the first stage. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Russian |
| تدمد: | 1994-4098 1999-8627 |
| Relation: | https://ojrs.abvpress.ru/ojrs/article/view/200; https://doaj.org/toc/1994-4098; https://doaj.org/toc/1999-8627 |
| DOI: | 10.17650/1994-4098-2011-0-4-64-67 |
| URL الوصول: | https://doaj.org/article/46ddfaa181774ac685e83c09ca3821a7 |
| رقم الأكسشن: | edsdoj.46ddfaa181774ac685e83c09ca3821a7 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 19944098 19998627 |
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| DOI: | 10.17650/1994-4098-2011-0-4-64-67 |