Introduction: Prurigo nodularis (PN) is a chronic skin disorder of unknown origin which has the features of small nodules and papules along with intolerable itch leading to ulcers, bleeding and sensory neural loss in affected area. PN has quite resemblance with Alasaka in Ayurveda, which is a vata-kapha pradhan kshudra kushtha. Case summary: A 50 years old male patient suffering from PN was being treated on the line of Ayurveda just before the beginning of COVID pandemic. Due to sudden surge of first wave of corona virus pandemic and lockdown in India, the planed virechana (purgation) therapy was interrupted. We shifted our plan to mild type of virechana and conservative therapy after a short break of 10 days at patients’ home. However, the case was responded very well and significant clinical improvement was observed in Dynamic Pruritus Score (DPS), Numerical Rating Scale (NRS), Visual Analogue Scale (VAS), Verbal Rating Scale (VRS), Pruritus Severity Scale (PSS), Hamilton Depression Rating Scale (HDRS) and Dermatology Life Quality Index (DLQI).
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