دورية أكاديمية
Gestational diabetes mellitus seems to be associatied with inflammation
| العنوان: | Gestational diabetes mellitus seems to be associatied with inflammation |
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| المؤلفون: | Ayla Aktulay, Yaprak Engin-Ustun, Mehmet Sahin Ozkan, Salim Erkaya, Mustafa Kara, Oktay Kaymak, Nuri Danisman |
| المصدر: | Acta Clinica Croatica, Vol 54., Iss 4., Pp 475-478 (2015) |
| بيانات النشر: | Sestre Milosrdnice University hospital, Institute of Clinical Medical Research, 2015. |
| سنة النشر: | 2015 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | CHI3L1 protein, human, Diabetes, gestational, Leukocyte count, Neutrophils – cytology, Lymphocytes – cytology, Blood platelets – cytology, Medicine |
| الوصف: | The aim of this study was to investigate whether gestational diabetes mellitus (GDM) is associated with inflammation by comparing serum levels of human chitinase-3-like protein 1 (YKL-40), neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR). This case control study included 29 pregnant women with GDM and 29 pregnant women with normal glucose tolerance matched for age (±2 years) and pre-pregnancy body mass index (±2 kg/m2). The YKL-40/CHI3L1 levels were measured, and NLR and PLR investigated. There were no statistically significant differences in maternal age, gestational age, gravidity and parity. Higher YKL-40 levels were recorded in pregnant women with GDM compared to control subjects (203 (65-300) ng/mL vs. 159.2 (14-290) ng/mL, p=0.007). NLR and PLR were significantly higher in GDM compared with control group. In conclusion, GDM is associated with high levels of YKL-40, NLR and PLR, which indicate inflammatory status. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0353-9466 1333-9451 |
| Relation: | http://hrcak.srce.hr/file/229170; https://doaj.org/toc/0353-9466; https://doaj.org/toc/1333-9451 |
| URL الوصول: | https://doaj.org/article/47b3f96c8ccc4103b8d1cbbe3fb77071 |
| رقم الأكسشن: | edsdoj.47b3f96c8ccc4103b8d1cbbe3fb77071 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 03539466 13339451 |
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