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Diagnostic accuracy of circular RNA for diabetes Mellitus: a systematic review and diagnostic Meta-analysis

التفاصيل البيبلوغرافية
العنوان: Diagnostic accuracy of circular RNA for diabetes Mellitus: a systematic review and diagnostic Meta-analysis
المؤلفون: Hojat Dehghanbanadaki, Pooria Asili, Abdolkarim Haji Ghadery, Maryam Mirahmad, Ali Zare Dehnavi, Amirhossein Parsaei, Hamid Reza Baradaran, Mobin Azami, Gustavo Jose Justo da Silva, Reza Parvan, Yousef Moradi
المصدر: BMC Medical Genomics, Vol 16, Iss 1, Pp 1-8 (2023)
بيانات النشر: BMC, 2023.
سنة النشر: 2023
المجموعة: LCC:Internal medicine
LCC:Genetics
مصطلحات موضوعية: circRNAs, Diabetes, Diagnosis, Biomarker, Meta-analysis, Internal medicine, RC31-1245, Genetics, QH426-470
الوصف: Abstract Background This study aimed to investigate the pooled diagnostic ability of circular RNA (circRNA) molecules for diabetes mellitus. Methods We searched PubMed, Scopus, and Web of Science for relevant studies. A total of 2070 participants, including 775 diabetic patients and 1295 healthy individuals, from five studies were included in this meta-analysis. True positive, true negative, false positive, and false negative data were extracted to calculate pooled sensitivity, specificity, positive and negative likelihood ratios, diagnostic odds ratio, and area under the receiver operating characteristics curve. The Deeks’ funnel plot was applied for publication bias assessment, Cochran’s Q test and I2 index were applied for inter-study heterogeneity assessment. Besides, a subgroup analysis was performed for determining the source of heterogeneity between studies. P value
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1755-8794
Relation: https://doaj.org/toc/1755-8794
DOI: 10.1186/s12920-023-01476-0
URL الوصول: https://doaj.org/article/47c2e597cf85443ca66c2e2168c40b49
رقم الأكسشن: edsdoj.47c2e597cf85443ca66c2e2168c40b49
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:17558794
DOI:10.1186/s12920-023-01476-0