دورية أكاديمية
Does Desmopressin Reduce Intraoperative Bleeding in Patients Who Undergo Nasal Surgery? A Systematic Review and Meta-Analysis
| العنوان: | Does Desmopressin Reduce Intraoperative Bleeding in Patients Who Undergo Nasal Surgery? A Systematic Review and Meta-Analysis |
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| المؤلفون: | Sun Hong Kim, Ah Young Bae, Do Hyun Kim, Se Hwan Hwang |
| المصدر: | Journal of Rhinology, Vol 31, Iss 1, Pp 8-16 (2024) |
| بيانات النشر: | Korean Rhinologic Society, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine LCC:Otorhinolaryngology |
| مصطلحات موضوعية: | deamino arginine vasopressin, endoscopes, nose, hemorrhage, meta-analysis, Medicine, Otorhinolaryngology, RF1-547 |
| الوصف: | Background and Objectives This study aimed to determine the efficacy of prophylactic desmopressin administered via the intranasal or intravenous route in reducing intraoperative bleeding during nasal surgery. We conducted a meta-analysis of the relevant literature to investigate the role of preoperative desmopressin in minimizing bleeding complications associated with nasal surgery. Methods We screened the relevant literature published before February 2023. Nine articles that compared the perioperative use of desmopressin (treatment) with a placebo or no treatment (control) were included. The analyzed outcomes were intraoperative bleeding during nasal surgery and postoperative morbidity. Results The treatment group showed significant improvements in intraoperative bleeding, the surgical field, and surgeon satisfaction compared to the control group. However, the prophylactic use of desmopressin was associated with elevated blood pressure and decreased serum sodium levels compared to the control group. Nonetheless, no significant adverse effects were reported in the included studies. Subgroup analyses comparing the route of administration (intravenous vs. intranasal) and type of surgery (rhinoplasty vs. endoscopic sinus surgery) showed that desmopressin had a beneficial effect on intraoperative bleeding and the surgical field, regardless of the route of administration or type of surgery. Conclusion The prophylactic use of desmopressin for nasal surgery effectively reduced intraoperative bleeding, improved the surgical field, and increased surgeon satisfaction, with no significant adverse effects. However, caution should be exercised when administering desmopressin as it may cause an elevation in postoperative blood pressure in patients with cardiopulmonary problems. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Korean |
| تدمد: | 1229-1498 2384-4361 |
| Relation: | http://www.j-rhinology.org/upload/pdf/jr-2024-00007.pdf; https://doaj.org/toc/1229-1498; https://doaj.org/toc/2384-4361 |
| DOI: | 10.18787/jr.2024.00007 |
| URL الوصول: | https://doaj.org/article/47f445a0b6dd4b60b45316140943ba88 |
| رقم الأكسشن: | edsdoj.47f445a0b6dd4b60b45316140943ba88 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 12291498 23844361 |
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| DOI: | 10.18787/jr.2024.00007 |