دورية أكاديمية

The Potential of a Sumbawa Herbal Oil-Based Oleogel as Burn Wound Dressing

التفاصيل البيبلوغرافية
العنوان: The Potential of a Sumbawa Herbal Oil-Based Oleogel as Burn Wound Dressing
المؤلفون: Andi Irma Yuniar, Nurul Wahidah Yasid, Syarifah Fatimah Nissatuljannah, Syamsu Rijal, Armanto Makmun
المصدر: Biology, Medicine & Natural Product Chemistry, Vol 12, Iss 2, Pp 559-562 (2023)
بيانات النشر: State Islamic University Sunan Kalijaga, 2023.
سنة النشر: 2023
المجموعة: LCC:Biology (General)
مصطلحات موضوعية: sumbawa herbal oil, oleogel, burn, wound dressing, Biology (General), QH301-705.5
الوصف: This study aimed to innovate the current Sumbawa oil preparation which is still in the form of liquid into an oleogel so that it is easier to apply and more practical for distribution and storage. Phytochemical analysis of Sumbawa oil showed the contents of phenols, flavonoids, and alkaloids. By adding hydroxyethyl cellulose (HEC) as a gelling agent and glycerin as a humectant, Sumbawa oil can be served in the form of an oleogel. The pH measurement of the Sumbawa oil oleogel at levels of 90%, 95%, and 100% ranged from 7.0–7.3 which is the ideal acidity level for the wound healing process. In the antimicrobial activity test with S. aureus and E. coli, the zone of inhibition ranged from 12.1–14.7 mm which is considered strong. Meanwhile, in in vitro testing of the anti-inflammatory activity using the human red blood cell membrane stabilization method, the stability level of each was obtained to be 78% for 100% Sumbawa oil, 74% for oleogel with 95% Sumbawa oil, and 73% for oleogel with 90% Sumbawa oil. The oleogel morphology observation using a scanning electron microscope showed a good gelation process at 5% and 10% HEC levels.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2089-6514
2540-9328
Relation: https://sciencebiology.org/index.php/BIOMEDICH/article/view/393; https://doaj.org/toc/2089-6514; https://doaj.org/toc/2540-9328
DOI: 10.14421/biomedich.2023.122.559-562
URL الوصول: https://doaj.org/article/482deeb9c3d7479f80e37e92c95ca5ce
رقم الأكسشن: edsdoj.482deeb9c3d7479f80e37e92c95ca5ce
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20896514
25409328
DOI:10.14421/biomedich.2023.122.559-562