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Radiation induced temporal lobe necrosis in nasopharyngeal cancer patients after radical external beam radiotherapy

التفاصيل البيبلوغرافية
العنوان: Radiation induced temporal lobe necrosis in nasopharyngeal cancer patients after radical external beam radiotherapy
المؤلفون: Vincent W. C. Wu, Shing-yau Tam
المصدر: Radiation Oncology, Vol 15, Iss 1, Pp 1-7 (2020)
بيانات النشر: BMC, 2020.
سنة النشر: 2020
المجموعة: LCC:Medical physics. Medical radiology. Nuclear medicine
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
مصطلحات موضوعية: Temporal lobe necrosis, Nasopharyngeal carcinoma, Radiotherapy, Radiation induced complication, Diagnosis and treatment, Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
الوصف: Abstract Radiation-induced temporal lobe necrosis (TLN) is one of the late post-radiotherapy complications in nasopharyngeal cancer (NPC) patients. Since NPC is common to have skull base infiltration, irradiation of the temporal lobes is inevitable despite the use of the more advanced intensity-modulated radiotherapy (IMRT). Moreover, the diagnosis and treatment of TLN remain challenging. In this review, we discuss the diagnosis of TLN with conventional and advanced imaging modalities, onset and predictive parameters of TLN development, the impact of IMRT on TLN in terms of incidence and dosimetric analyzes, and the recent advancements in the treatment of TLN.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1748-717X
Relation: http://link.springer.com/article/10.1186/s13014-020-01560-0; https://doaj.org/toc/1748-717X
DOI: 10.1186/s13014-020-01560-0
URL الوصول: https://doaj.org/article/c483b2574f964ec4be28be96c0d9e2f3
رقم الأكسشن: edsdoj.483b2574f964ec4be28be96c0d9e2f3
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:1748717X
DOI:10.1186/s13014-020-01560-0