دورية أكاديمية
Soft Surface Nanostructure with Semi-Free Polyionic Components for Sustainable Antimicrobial Plastic
| العنوان: | Soft Surface Nanostructure with Semi-Free Polyionic Components for Sustainable Antimicrobial Plastic |
|---|---|
| المؤلفون: | Shook Pui Chan, Diane S. W. Lim, Arunmozhiarasi Armugam, Guangshun Yi, Yugen Zhang |
| المصدر: | International Journal of Molecular Sciences, Vol 22, Iss 22, p 12315 (2021) |
| بيانات النشر: | MDPI AG, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Biology (General) LCC:Chemistry |
| مصطلحات موضوعية: | antimicrobial plastic, sustainable material, surface phase seperation, surface nanostructure, semi-free polyionic, Biology (General), QH301-705.5, Chemistry, QD1-999 |
| الوصف: | Surface antimicrobial materials are of interest as they can combat the critical threat of microbial contamination without contributing to issues of environmental contamination and the development drug resistance. Most nanostructured surfaces are prepared by post fabrication modifications and actively release antimicrobial agents. These properties limit the potential applications of nanostructured materials on flexible surfaces. Here, we report on an easily synthesized plastic material with inherent antimicrobial activity, demonstrating excellent microbicidal properties against common bacteria and fungus. The plastic material did not release antimicrobial components as they were anchored to the polymer chains via strong covalent bonds. Time-kill kinetics studies have shown that bactericidal effects take place when bacteria come into contact with a material for a prolonged period, resulting in the deformation and rupture of bacteria cells. A scanning probe microscopy analysis revealed soft nanostructures on the submicron scale, for which the formation is thought to occur via surface phase separation. These soft nanostructures allow for polyionic antimicrobial components to be present on the surface, where they freely interact with and kill microbes. Overall, the new green and sustainable plastic is easily synthesized and demonstrates inherent and long-lasting activity without toxic chemical leaching. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1422-0067 1661-6596 |
| Relation: | https://www.mdpi.com/1422-0067/22/22/12315; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067 |
| DOI: | 10.3390/ijms222212315 |
| URL الوصول: | https://doaj.org/article/c488749bcb174856951fba9ea883cff7 |
| رقم الأكسشن: | edsdoj.488749bcb174856951fba9ea883cff7 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14220067 16616596 |
|---|---|
| DOI: | 10.3390/ijms222212315 |