دورية أكاديمية
A feasibility study on utilizing machine learning technology to reduce the costs of gastric cancer screening in Taizhou, China
| العنوان: | A feasibility study on utilizing machine learning technology to reduce the costs of gastric cancer screening in Taizhou, China |
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| المؤلفون: | Si-yan Yan, Xin-yu Fu, Shen-Ping Tang, Rong-bin Qi, Jia-wei Liang, Xin-li Mao, Li-ping Ye, Shao-wei Li |
| المصدر: | Digital Health, Vol 10 (2024) |
| بيانات النشر: | SAGE Publishing, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Computer applications to medicine. Medical informatics |
| مصطلحات موضوعية: | Computer applications to medicine. Medical informatics, R858-859.7 |
| الوصف: | Aim To optimize gastric cancer screening score and reduce screening costs using machine learning models. Methods This study included 228,634 patients from the Taizhou Gastric Cancer Screening Program. We used three machine learning models to optimize Li's gastric cancer screening score: Gradient Boosting Machine (GBM), Distributed Random Forest (DRF), and Deep Learning (DL). The performance of the binary classification models was evaluated using the area under the curve (AUC) and area under the precision–recall curve (AUCPR). Results In the binary classification model used to distinguish low-risk and moderate- to high-risk patients, the AUC in the GBM, DRF, and DL full models were 0.9994, 0.9982, and 0.9974, respectively, and the AUCPR was 0.9982, 0.9949, and 0.9918, respectively. Excluding Helicobacter pylori IgG antibody, pepsinogen I, and pepsinogen II, the AUC in the GBM, DRF, and DL models were 0.9932, 0.9879, and 0.9900, respectively, and the AUCPR was 0.9835, 0.9716, and 0.9752, respectively. Remodel after removing variables IgG, PGI, PGII, and G-17, the AUC in GBM, DRF, and DL was 0.8524, 0.8482, 0.8477, and AUCPR was 0.6068, 0.6008, and 0.5890, respectively. When constructing a tri-classification model, we discovered that none of the three machine learning models could effectively distinguish between patients at intermediate and high risk for gastric cancer (F1 scores in the GBM model for the low, medium and high risk: 0.9750, 0.9193, 0.5334, respectively; F1 scores in the DRF model for low, medium, and high risks: 0.9888, 0.9479, 0.6694, respectively; F1 scores in the DL model for low, medium, and high risks: 0.9812, 0.9216, 0.6394, respectively). Conclusion We concluded that gastric cancer screening indicators could be optimized when distinguishing low-risk and moderate to high-risk populations, and detecting gastrin-17 alone can achieve a good discriminative effect, thus saving huge expenditures. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2055-2076 20552076 |
| Relation: | https://doaj.org/toc/2055-2076 |
| DOI: | 10.1177/20552076241277713 |
| URL الوصول: | https://doaj.org/article/49208c08c1084ea9af75d4a5eca9975f |
| رقم الأكسشن: | edsdoj.49208c08c1084ea9af75d4a5eca9975f |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20552076 |
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| DOI: | 10.1177/20552076241277713 |