دورية أكاديمية

The effect of non-pharmaceutical interventions on COVID-19 outcomes: A heterogeneous age-related generalisation of the SEIR model

التفاصيل البيبلوغرافية
العنوان: The effect of non-pharmaceutical interventions on COVID-19 outcomes: A heterogeneous age-related generalisation of the SEIR model
المؤلفون: Jorge M. Mendes, Pedro S. Coelho
المصدر: Infectious Disease Modelling, Vol 8, Iss 3, Pp 742-768 (2023)
بيانات النشر: KeAi Communications Co., Ltd., 2023.
سنة النشر: 2023
المجموعة: LCC:Infectious and parasitic diseases
مصطلحات موضوعية: Infectious and parasitic diseases, RC109-216
الوصف: Successive generalisations of the basic SEIR model have been proposed to accommodate the different needs of the organisations handling the SARS-CoV-2 epidemic and the assessment of the public health measures adopted and named under the common umbrella of Non-Pharmaceutical Interventions (NPIs). So far, these generalisations have not been able to assess the ability of these measures to avoid infection by the SARS-CoV-2 and thus their contribution to contain the spread of the disease. This work proposes a new generalisation of SEIR model and includes a heterogeneous and age-related generation of infections that depends both on a probability that a contact generates the transmission of the disease and a contact rate. The results show (1) thanks to the universal wearing of facial coverings, the probability that a contact provokes the transmission of the disease was reduced by at least 50% and (2) the impact of the other NPI is so significant that otherwise Portugal would have gone into a non-sustainable situation of having 80% of its population infected in the first 300 days of the pandemic. This situation would have led to a number of deaths almost twenty times higher than the number that was actually recorded by December 26th, 2020. Moreover, the results suggest that even if the requirement of universal wearing of facial coverings was adopted sooner jointly with closing workplaces and resorting to teleworking would have postponed the peak of the incidence, altought the epidemic path would have result in a number of infections hardly managed by the National Health System. Complementary, results confirm that (3) the health authorities adopted a conservative approach on the criteria to consider an infected individual not infective any longer; and (4) the most effective NPIs and stringency levels either impacting on self-protection against infection or reducing the contacts that would eventually result in infection are, in decreasing order of importance, the use of Facial coverings, Workplace closing and Stay at home requirements.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2468-0427
Relation: http://www.sciencedirect.com/science/article/pii/S2468042723000441; https://doaj.org/toc/2468-0427
DOI: 10.1016/j.idm.2023.05.009
URL الوصول: https://doaj.org/article/494ba0551e424701b4de9a46f6ca131f
رقم الأكسشن: edsdoj.494ba0551e424701b4de9a46f6ca131f
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:24680427
DOI:10.1016/j.idm.2023.05.009