دورية أكاديمية
Long-Term Survival Effects of Preoperative Breast MRI in Patients with Breast-Conserving Surgery
العنوان: | Long-Term Survival Effects of Preoperative Breast MRI in Patients with Breast-Conserving Surgery |
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المؤلفون: | Ahmet Serkan Ilgun, Dauren Sarsenov, Gul Alco, Alper Ozturk, Filiz Agacayak, Filiz Elbuken, Zeynep Erdogan, Kezban Nur Pilanci, Cetin Ordu, Fatma Aktepe, Gursel Soybir, Vahit Ozmen |
المصدر: | Acta Clinica Croatica, Vol 61., Iss 1., Pp 30-37 (2022) |
بيانات النشر: | Sestre Milosrdnice University hospital, Institute of Clinical Medical Research, 2022. |
سنة النشر: | 2022 |
المجموعة: | LCC:Medicine |
مصطلحات موضوعية: | Breast cancer, Breast MRI, Breast-conserving surgery, Overall survival, Local failure, Oncologic outcome, Medicine |
الوصف: | The benefit of breast magnetic resonance imaging (MRI) in breast-conserving surgery (BCS) is unclear. Our study compared breast cancer patients with and without preoperative breast MRI and their long-term oncologic outcomes are reported. A total of 1378 BCS cases with early breast cancer between 1996 and 2017 were reviewed. Patients with carcinoma in situ or neoadjuvant treatment or having breast MRI after tumor excision were excluded. Of 1378 patients, 270 (19.5%) had preoperative MRI. There were no significant differences regarding T and N stage and molecular subtypes between the groups. Surgical margins were significantly wider in the breast MRI group. Five-year overall survival (OS) was 96.9% in the MRI group and 94.3% in the control group, and this difference was not significant (p=0.11). Five-year local-regional recurrence-free survival (LRFS) was not significantly different either (98.8% and 96.5%, respectively, p=0.41). When analyses were repeated only for patients with hormone receptor-negative or triple-negative breast cancer, there was still no significant difference in OS, LRFS, or disease-free survival. In conclusion, MRI does not seem necessary in all patients undergoing BCS. New prospective randomized controlled trials are needed to determine appropriate use of preoperative MRI and its effects on oncologic outcomes in early breast cancer patients. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 0353-9466 1333-9451 |
Relation: | https://hrcak.srce.hr/file/405837; https://doaj.org/toc/0353-9466; https://doaj.org/toc/1333-9451 |
DOI: | 10.20471/acc.2022.61.01.04 |
URL الوصول: | https://doaj.org/article/49c012c77ce44d38a3de008b0633df30 |
رقم الأكسشن: | edsdoj.49c012c77ce44d38a3de008b0633df30 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 03539466 13339451 |
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DOI: | 10.20471/acc.2022.61.01.04 |