دورية أكاديمية
Diversity in Oncology Clinical Trials: Current Landscape for Industry-Sponsored Clinical Trials in Asia
| العنوان: | Diversity in Oncology Clinical Trials: Current Landscape for Industry-Sponsored Clinical Trials in Asia |
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| المؤلفون: | Dany Habr, Manmohan Singh, Roberto Uehara |
| المصدر: | Oncology and Therapy, Vol 12, Iss 1, Pp 115-129 (2023) |
| بيانات النشر: | Adis, Springer Healthcare, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: | Asia, Clinical trials, Diversity, Industry-sponsored, Oncology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Abstract Introduction There has been a growing recognition on the importance of diversity in clinical trials. Existing research has highlighted a significant demographic imbalance. Amidst this renewed focus on diversity, it is crucial to acknowledge that Asia comprises over half of the world’s population. Given the region’s demographic significance, we sought to compare various characteristics and growth rates for trials with sites in Asia against those without any sites in Asia. Methods We performed comprehensive analyses of industry-sponsored phase 2 and 3 oncology trials registered at Clinicaltrials.gov, using drugs or biologics as investigational agents and executed between 1 January 2018 and 31 December 2022. We applied the compound annual growth rate (CAGR) as an analytical tool to track the trial growth rates over this 5-year period. Results We identified 894 industry-sponsored phase 2 and 3 cancer studies with available study location data. Out of these, 415 trials (46.42%) had study sites in Asia. Notably, these trials with sites in Asia were also more likely to be phase 3 trials (39.76% vs 6.47%, p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2366-1070 2366-1089 |
| Relation: | https://doaj.org/toc/2366-1070; https://doaj.org/toc/2366-1089 |
| DOI: | 10.1007/s40487-023-00254-3 |
| URL الوصول: | https://doaj.org/article/4a01c1547a3942f3b81f3272149ca898 |
| رقم الأكسشن: | edsdoj.4a01c1547a3942f3b81f3272149ca898 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 23661070 23661089 |
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| DOI: | 10.1007/s40487-023-00254-3 |