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Precise pulmonary scanning and reducing medical radiation exposure by developing a clinically applicable intelligent CT system: Toward improving patient care

التفاصيل البيبلوغرافية
العنوان: Precise pulmonary scanning and reducing medical radiation exposure by developing a clinically applicable intelligent CT system: Toward improving patient care
المؤلفون: Yang Wang, Xiaofan Lu, Yingwei Zhang, Xin Zhang, Kun Wang, Jiani Liu, Xin Li, Renfang Hu, Xiaolin Meng, Shidan Dou, Huayin Hao, Xiaofen Zhao, Wei Hu, Cheng Li, Yaozong Gao, Zhishun Wang, Guangming Lu, Fangrong Yan, Bing Zhang
المصدر: EBioMedicine, Vol 54, Iss , Pp - (2020)
بيانات النشر: Elsevier, 2020.
سنة النشر: 2020
المجموعة: LCC:Medicine
LCC:Medicine (General)
مصطلحات موضوعية: Medicine, Medicine (General), R5-920
الوصف: Background: Interstitial lung disease requires frequent re-examination, which directly causes excessive cumulative radiation exposure. To date, AI has not been applied to CT for enhancing clinical care; thus, we hypothesize AI may empower CT with intelligence to realize automatic and accurate pulmonary scanning, thus dramatically decrease medical radiation exposure without compromising patient care. Methods: Facial boundary detection was realized by recognizing adjacent jaw position through training and testing a region proposal network (RPN) on 76,882 human faces using a preinstalled 2-dimensional camera; the lung-fields was then segmented by V-Net on another training set with 314 subjects and calculated the moving distance of the scanning couch based on a pre-generated calibration table. A multi-cohort study, including 1,186 patients was used for validation and radiation dose quantification under three clinical scenarios. Findings: A U-HAPPY (United imaging Human Automatic Planbox for PulmonarY) scanning CT was designed. Error distance of RPN was 4·46±0·02 pixels with a success rate of 98·7% in training set and 2·23±0·10 pixels with 100% success rate in testing set. Average Dice's coefficient was 0·99 in training set and 0·96 in testing set. A calibration table with 1,344,000 matches was generated to support the linkage between camera and scanner. This real-time automation makes an accurate plan-box to cover exact location and area needed to scan, thus reducing amounts of radiation exposures significantly (all, P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2352-3964
Relation: http://www.sciencedirect.com/science/article/pii/S2352396420300992; https://doaj.org/toc/2352-3964
DOI: 10.1016/j.ebiom.2020.102724
URL الوصول: https://doaj.org/article/4a0bd25af07e47888cc69aba87130c7b
رقم الأكسشن: edsdoj.4a0bd25af07e47888cc69aba87130c7b
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:23523964
DOI:10.1016/j.ebiom.2020.102724