دورية أكاديمية
GENETIC POLYMORPHISM OF INFLAMMATORY FACTORS IS ASSOCIATED WITH THROMBOEMBOLIC COMPLICATIONS OF ATRIAL FIBRILLATION
| العنوان: | GENETIC POLYMORPHISM OF INFLAMMATORY FACTORS IS ASSOCIATED WITH THROMBOEMBOLIC COMPLICATIONS OF ATRIAL FIBRILLATION |
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| المؤلفون: | I. V. Zotova, A. N. Brovkin, E. N. Fattakhova, A. N. Nikitin, V. V. Nosikov, V. A. Brazhnik, D. A. Zateyshchikov |
| المصدر: | Российский кардиологический журнал, Vol 0, Iss 10, Pp 35-41 (2015) |
| بيانات النشر: | «FIRMA «SILICEA» LLC, 2015. |
| سنة النشر: | 2015 |
| المجموعة: | LCC:Diseases of the circulatory (Cardiovascular) system |
| مصطلحات موضوعية: | atrial fibrillation, inflammation factors polymorphism, interleukin 6 receptor gene polymorphism, stroke risk, thrombosis risk, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: | Aim. To reveal the association of hereditary specifics of inflammatory factors with the adverse risk in atrial fibrillation (AF).Material and methods. Totally 258 patients studied (68,5±0,67 y. o.) with nonvalvular AF, recording the events as ischemic stroke, myocardial infarction, venous and arterial thromboembolism. Mean follow-up was 455±11,71 days.Results. Factors that are independently associated with ischemic stroke development in patients not receiving anticoagulants (n=101), were the allele C of polymorphic marker rs2228145(А/С) of gene IL-6 receptor (OR 13,25 CI 1,57112,18, р=0,018), age ?75 y. o. (OR 1,1, CI 1,008-1,2, р=0,032) and EF LV (OR 0,97 CI 0,94-0,99 р=0,027), with a “thrombotic endpoint” development — DM (OR 4,3 CI 1,46-12,45 р=0,008), EF LV (OR 0,96 CI 0,94-0,98, р |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Russian |
| تدمد: | 1560-4071 2618-7620 |
| Relation: | https://russjcardiol.elpub.ru/jour/article/view/295; https://doaj.org/toc/1560-4071; https://doaj.org/toc/2618-7620 |
| DOI: | 10.15829/1560-4071-2015-10-35-41 |
| URL الوصول: | https://doaj.org/article/4a8dd4cd9fc24807ba9d471a31cd8f25 |
| رقم الأكسشن: | edsdoj.4a8dd4cd9fc24807ba9d471a31cd8f25 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 15604071 26187620 |
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| DOI: | 10.15829/1560-4071-2015-10-35-41 |