دورية أكاديمية

Analysis of clinical characteristics and laboratory findings of 95 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a retrospective analysis

التفاصيل البيبلوغرافية
العنوان: Analysis of clinical characteristics and laboratory findings of 95 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a retrospective analysis
المؤلفون: Gemin Zhang, Jie Zhang, Bowen Wang, Xionglin Zhu, Qiang Wang, Shiming Qiu
المصدر: Respiratory Research, Vol 21, Iss 1, Pp 1-10 (2020)
بيانات النشر: BMC, 2020.
سنة النشر: 2020
المجموعة: LCC:Diseases of the respiratory system
مصطلحات موضوعية: 2019 novel coronavirus, Pneumonia, Clinical characteristics, Laboratory findings, Diseases of the respiratory system, RC705-779
الوصف: Abstract Background Since December 2019, 2019 novel coronavirus pneumonia emerged in Wuhan city and rapidly spread throughout China and even the world. We sought to analyse the clinical characteristics and laboratory findings of some cases with 2019 novel coronavirus pneumonia . Methods In this retrospective study, we extracted the data on 95 patients with laboratory-confirmed 2019 novel coronavirus pneumonia in Wuhan Xinzhou District People’s Hospital from January 16th to February 25th, 2020. Cases were confirmed by real-time RT-PCR and abnormal radiologic findings. Outcomes were followed up until March 2th, 2020. Results Higher temperature, blood leukocyte count, neutrophil count, neutrophil percentage, C-reactive protein level, D-dimer level, alanine aminotransferase activity, aspartate aminotransferase activity, α - hydroxybutyrate dehydrogenase activity, lactate dehydrogenase activity and creatine kinase activity were related to severe 2019 novel coronavirus pneumonia and composite endpoint, and so were lower lymphocyte count, lymphocyte percentage and total protein level. Age below 40 or above 60 years old, male, higher Creatinine level, and lower platelet count also seemed related to severe 2019 novel coronavirus pneumonia and composite endpoint, however the P values were greater than 0.05, which mean under the same condition studies of larger samples are needed in the future. Conclusion Multiple factors were related to severe 2019 novel coronavirus pneumonia and composite endpoint, and more related studies are needed in the future.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1465-993X
Relation: http://link.springer.com/article/10.1186/s12931-020-01338-8; https://doaj.org/toc/1465-993X
DOI: 10.1186/s12931-020-01338-8
URL الوصول: https://doaj.org/article/4c0b143fd11a4e59ac96117ccb24fe0e
رقم الأكسشن: edsdoj.4c0b143fd11a4e59ac96117ccb24fe0e
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:1465993X
DOI:10.1186/s12931-020-01338-8