دورية أكاديمية
أعرض في EDS

Serum Allergen-Specific Immunoglobulin E in Cats with Inflammatory Bronchial Disease

التفاصيل البيبلوغرافية
العنوان: Serum Allergen-Specific Immunoglobulin E in Cats with Inflammatory Bronchial Disease
المؤلفون: Lina Hörner-Schmid, Jelena Palić, Ralf S. Mueller, Bianka Schulz
المصدر: Animals, Vol 13, Iss 20, p 3226 (2023)
بيانات النشر: MDPI AG, 2023.
سنة النشر: 2023
المجموعة: LCC:Veterinary medicine
LCC:Zoology
مصطلحات موضوعية: airways, feline asthma, chronic bronchitis, immunology, ELISA, allergy, Veterinary medicine, SF600-1100, Zoology, QL1-991
الوصف: The etiology of feline inflammatory bronchial disease is poorly understood. This study compares the degree of allergen-specific serum IgE responses between cats with feline asthma, chronic bronchitis, mixed inflammation, and clinically healthy cats (HCs). The retrospective case–control study used serum from eighteen cats with eosinophilic inflammation (EI), ten with neutrophilic inflammation (NI), six with mixed inflammation (MI), and fourteen HCs. Affected cats were categorized into groups based on bronchoalveolar lavage cytology. The measurement of IgE for 34 different allergens including fungal organisms, weeds, grasses, trees, mites, and insects was performed using an indirect ELISA. Positive reactions to allergens were detected in the serum of 17/18 cats with EI, 8/10 with NI, 6/6 with MI, and 11/14 HCs (p = 0.364). When overall positive reactions were compared between groups, cats with MI (p = p = 0.014). Sensitization against dust mites seems to be more prevalent in cats with MI. However, positive IgE reactions can be observed in healthy and diseased cats, and, therefore, need to be interpreted in the light of clinical findings and environmental conditions of individual patients.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2076-2615
Relation: https://www.mdpi.com/2076-2615/13/20/3226; https://doaj.org/toc/2076-2615
DOI: 10.3390/ani13203226
URL الوصول: https://doaj.org/article/4c62543abc974259ae69458f11a7e835
رقم الأكسشن: edsdoj.4c62543abc974259ae69458f11a7e835
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20762615
DOI:10.3390/ani13203226