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Persistent Sexual, Emotional, and Cognitive Impairment Post-Finasteride

التفاصيل البيبلوغرافية
العنوان: Persistent Sexual, Emotional, and Cognitive Impairment Post-Finasteride
المؤلفون: Christine Anne Ganzer PhD, Alan Roy Jacobs MD, Farin Iqbal
المصدر: American Journal of Men's Health, Vol 9 (2015)
بيانات النشر: SAGE Publishing, 2015.
سنة النشر: 2015
المجموعة: LCC:Medicine
مصطلحات موضوعية: Medicine
الوصف: Finasteride is a synthetic 5-α reductase inhibitor, which prevents the conversion of testosterone to dihydrotestosterone and has been used for more than 20 years in the treatment of male pattern hair loss. Randomized, controlled trials have associated finasteride with both reversible and persistent adverse effects. In this pilot study, we sought to characterize sexual and nonsexual adverse effects that men reported experiencing at least 3 months after stopping the medication. Based on previous research on persistent side effects of finasteride, we constructed an Internet survey targeting six domains: physical symptoms, sexual libido, ejaculatory disorders, disorders of the penis and testes, cognitive symptoms, and psychological symptoms and was e-mailed to patients who reported experiencing symptoms of side effects of finasteride. Responses from 131 generally healthy men (mean age, 24 years) who had taken finasteride for male pattern hair loss was included in the analysis. The most notable finding was that adverse effects persisted in each of the domains, indicating the possible presence of a “post-finasteride syndrome.”
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1557-9883
1557-9891
15579883
Relation: https://doaj.org/toc/1557-9883; https://doaj.org/toc/1557-9891
DOI: 10.1177/1557988314538445
URL الوصول: https://doaj.org/article/d4cde649f7f04f09a61562c177ed338f
رقم الأكسشن: edsdoj.4cde649f7f04f09a61562c177ed338f
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:15579883
15579891
DOI:10.1177/1557988314538445