دورية أكاديمية
Specific effects on the thyroid relevant for performing a dietary cumulative risk assessment of pesticide residues: 2024 update
| العنوان: | Specific effects on the thyroid relevant for performing a dietary cumulative risk assessment of pesticide residues: 2024 update |
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| المؤلفون: | European Food Safety Authority (EFSA), Federica Crivellente, Antonio F. Hernández‐Jerez, Anna Lanzoni, Francesca Metruccio, Luc Mohimont, Dimitra Nikolopoulou, Anna F. Castoldi |
| المصدر: | EFSA Journal, Vol 22, Iss 3, Pp n/a-n/a (2024) |
| بيانات النشر: | Wiley, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Nutrition. Foods and food supply LCC:Chemical technology |
| مصطلحات موضوعية: | cumulative risk assessment, cumulative toxicity, endocrine, hypothyroidism, pesticide residues, thyroid, Nutrition. Foods and food supply, TX341-641, Chemical technology, TP1-1185 |
| الوصف: | Abstract EFSA updated its previous work on the establishment of specific effects that are considered relevant for grouping pesticide residues targeting the thyroid and for performing the retrospective assessment of dietary cumulative risk (CRA). The two specific effects already selected in 2019 leading to the two cumulative assessment groups (CAGs) ‘hypothyroidism’ and ‘C‐cell hypertrophy, hyperplasia and neoplasia’ were reconfirmed. Compared to 2019, the list of indicators that can be used to identify these specific effects was refined to only include histopathological changes. In a second phase of the work, data will be extracted on indicators of the specific effects from the dossiers on active substances (a.s.) used as plant protection products. The criteria for including a.s. into CAGs were also updated, together with the hazard characterisation methodology and the lines of evidence for assessing CAG‐membership probabilities. The tasks related to the data extraction and the establishment of the CAGs on hypothyroidism and on C‐cell hypertrophy, hyperplasia and neoplasia are beyond the scope of this report. This part of the CRA process has been outsourced and will be the subject of a separate report. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1831-4732 |
| Relation: | https://doaj.org/toc/1831-4732 |
| DOI: | 10.2903/j.efsa.2024.8672 |
| URL الوصول: | https://doaj.org/article/4e14daa56d30446095859d45c0585aef |
| رقم الأكسشن: | edsdoj.4e14daa56d30446095859d45c0585aef |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 18314732 |
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| DOI: | 10.2903/j.efsa.2024.8672 |