دورية أكاديمية
Influence of Maceration Solvent on Chemical Composition of Gemmotherapy Macerates—A Case Study on Olea europaea Young Shoots
| العنوان: | Influence of Maceration Solvent on Chemical Composition of Gemmotherapy Macerates—A Case Study on Olea europaea Young Shoots |
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| المؤلفون: | Dimitri Bréard, Hélène Esselin, Lucie Bugeia, Séverine Boisard, David Guilet, Pascal Richomme, Anne-Marie Le Ray, Christophe Ripoll |
| المصدر: | Nutraceuticals, Vol 3, Iss 4, Pp 574-590 (2023) |
| بيانات النشر: | MDPI AG, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Nutrition. Foods and food supply LCC:Nutritional diseases. Deficiency diseases |
| مصطلحات موضوعية: | gemmotherapy, bud, Olea europaea, phytochemical analysis, Nutrition. Foods and food supply, TX341-641, Nutritional diseases. Deficiency diseases, RC620-627 |
| الوصف: | Gemmotherapy, a natural therapy based on bud macerates, has recently gained importance in the field of food supplements. However, two coexisting extraction methods employ a glycerin-based solvent, either in a binary or ternary solvent mixture. The absence of an official method for bud preparation leads to non-standardized bud macerates. Given this context, this study aimed to (i) assess the influence of solvent composition on the chemical profile of olive young shoot macerates obtained using glycerin-based solvents or using different solvent extractions and (ii) to compare the two coexisting traditional bud extraction methods described by Dr Pol Henry and by the European Pharmacopoeia. A comprehensive phytochemical analysis of all macerates was conducted using HPLC-DAD-ELSD-MS2, identifying 50 metabolites divided into 7 classes through dereplication. The extracts obtained with the solvent described by the European Pharmacopoeia (ethanol/glycerin) and by Dr Pol Henry (water/ethanol/glycerin) appeared to be the most diversified in terms of metabolite distribution and possessed higher rates of secondary metabolites. These observations reinforce the interest in a glycerin-based solvent mixture for bud extraction in gemmotherapy. In addition, the difference in composition between the two traditional solvents was highlighted. Indeed, iridoids were predominant in both macerates, representing about 50% of the chemical composition, but differences were observed from one macerate to another regarding the proportions of the other chemical classes. This emphasizes the necessity for standardized gemmotherapy macerates. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1661-3821 |
| Relation: | https://www.mdpi.com/1661-3821/3/4/41; https://doaj.org/toc/1661-3821 |
| DOI: | 10.3390/nutraceuticals3040041 |
| URL الوصول: | https://doaj.org/article/4e679ac0080048fe9f82e602fd6ebbc5 |
| رقم الأكسشن: | edsdoj.4e679ac0080048fe9f82e602fd6ebbc5 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16613821 |
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| DOI: | 10.3390/nutraceuticals3040041 |