دورية أكاديمية
أعرض في EDS

Changing Patterns of Disease Severity in Blastomyces dermatitidis Infection, Quebec, Canada

التفاصيل البيبلوغرافية
العنوان: Changing Patterns of Disease Severity in Blastomyces dermatitidis Infection, Quebec, Canada
المؤلفون: Alex Carignan, Chiheb Boudhrioua, Sandrine Moreira, Andrée Ann Pelletier, Kevin Dufour, Jacques Pépin, Catherine Allard, Dominique Marcoux, Philippe J. Dufresne
المصدر: Emerging Infectious Diseases, Vol 27, Iss 11, Pp 2810-2817 (2021)
بيانات النشر: Centers for Disease Control and Prevention, 2021.
سنة النشر: 2021
المجموعة: LCC:Medicine
LCC:Infectious and parasitic diseases
مصطلحات موضوعية: blastomycosis, Blastomyces dermatitidis, mortality, severity, epidemiology, fungi, Medicine, Infectious and parasitic diseases, RC109-216
الوصف: This retrospective multicenter cohort study assessed temporal changes in the severity and mortality rate of blastomycosis in Quebec, Canada, and identified risk factors for death in patients with blastomycosis in 1988–2016. The primary outcome was 90-day all-cause deaths. Among 185 patients, 122 (66%) needed hospitalization and 30 (16%) died. We noted increases in the proportion of severe cases, in age at diagnosis and in the proportion of diabetic and immunocompromised patients over time. Independent risk factors for death were age (adjusted odds ratio [aOR] 1.04, 95% CI 1.00–1.07), immunosuppression (aOR 4.2, 95% CI 1.5–11.6), and involvement of >2 lung lobes (aOR 5.3, 95% CI 1.9–14.3). There was no association between the Blastomyces genotype group and all-cause mortality. The proportion of severe cases of blastomycosis has increased in Quebec over the past 30 years, partially explained by the higher number of immunosuppressed patients.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1080-6040
1080-6059
Relation: https://wwwnc.cdc.gov/eid/article/27/11/21-0552_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059
DOI: 10.3201/eid2711.210552
URL الوصول: https://doaj.org/article/4e999c9261cc448f93fb416db5d5e0fe
رقم الأكسشن: edsdoj.4e999c9261cc448f93fb416db5d5e0fe
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:10806040
10806059
DOI:10.3201/eid2711.210552