دورية أكاديمية

Epidemiological and clinical characteristics of 161 discharged cases with coronavirus disease 2019 in Shanghai, China

التفاصيل البيبلوغرافية
العنوان: Epidemiological and clinical characteristics of 161 discharged cases with coronavirus disease 2019 in Shanghai, China
المؤلفون: Sheng Lin, Hao Pan, Huanyu Wu, Xiao Yu, Peng Cui, Ruobing Han, Chenyan Jiang, Dechuan Kong, Yaxu Zheng, Xiaohuan Gong, Wenjia Xiao, Shenghua Mao, Bihong Jin, Yiyi Zhu, Xiaodong Sun
المصدر: BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-10 (2020)
بيانات النشر: BMC, 2020.
سنة النشر: 2020
المجموعة: LCC:Infectious and parasitic diseases
مصطلحات موضوعية: Coronavirus disease 2019, Epidemiology, Clinical characteristics, Transmission, First-level public health emergency response, Infectious and parasitic diseases, RC109-216
الوصف: Abstract Background In December 2019, the outbreak of coronavirus disease 2019 (COVID-19) began in Wuhan, China, and rapidly spread to other regions. We aimed to further describe the epidemiological and clinical characteristics of discharged COVID-19 cases and evaluate the public health interventions. Methods We collected epidemiological and clinical data of all discharged COVID-19 cases as of 17 February 2020 in Shanghai. The key epidemiological distributions were estimated and outcomes were also compared between patients whose illness were before 24 January and those whose illness were after 24 January. Results Of 161 discharged COVID-19 cases, the median age was 45 years, and 80 (49.7%) cases were male. All of the cases were categorized as clinical moderate type. The most common initial symptoms were fever (85.7%), cough (41.0%), fatigue (19.3%), muscle ache (17.4%), sputum production (14.9%), and there were six asymptomatic cases. 39 (24.2%) cases got infected in Shanghai, and three of them were second-generation cases of Shanghai native cases. The estimated median of the time from onset to first medical visit, admission, disease confirmation, and discharge for 161 cases was 1.0 day (95% CI, 0.6–1.2), 2.0 days (95% CI, 1.5–2.6), 5.2 days (95% CI, 4.6–5.7), 18.1 days (95% CI, 17.4–18.8), respectively. The estimated median of the time from admission to discharge was 14.0 days (95% CI, 13.3–14.6). The time from onset to first medical visit, admission and disease confirmation were all shortened after the Shanghai’s first-level public health emergency response. In Cox regression model, the significant independent covariates for the duration of hospitalization were age, the time from onset to admission and the first-level public health emergency response. Conclusions Local transmission had occurred in Shanghai in late January 2020. The estimated median of the time from onset to discharge of moderate COVID-19 was 18.1 days in Shanghai. Time intervals from onset to first medical visit, admission and disease confirmation were all shortened after the Shanghai’s first-level public health emergency response. Age, the first-level public health emergency response and the time from onset to admission were the impact factors for the duration of hospitalization.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1471-2334
Relation: http://link.springer.com/article/10.1186/s12879-020-05493-7; https://doaj.org/toc/1471-2334
DOI: 10.1186/s12879-020-05493-7
URL الوصول: https://doaj.org/article/c4eb94534f8b4e7cbc9247f5320d63c0
رقم الأكسشن: edsdoj.4eb94534f8b4e7cbc9247f5320d63c0
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14712334
DOI:10.1186/s12879-020-05493-7