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Can uric acid blood levels in renal transplant recipients predict allograft outcome?

التفاصيل البيبلوغرافية
العنوان: Can uric acid blood levels in renal transplant recipients predict allograft outcome?
المؤلفون: Ofer Isakov, Bhanu K. Patibandla, Doron Shwartz, Eytan Mor, Kenneth B. Christopher, Tammy Hod
المصدر: Renal Failure, Vol 43, Iss 1, Pp 1240-1249 (2021)
بيانات النشر: Taylor & Francis Group, 2021.
سنة النشر: 2021
المجموعة: LCC:Diseases of the genitourinary system. Urology
مصطلحات موضوعية: hyperuricemia, renal allograft function, renal allograft survival, mortality, Diseases of the genitourinary system. Urology, RC870-923
الوصف: Background Hyperuricemia is common after renal transplantation, especially in those receiving calcineurin inhibitors. Little, however, is known about the relationship between uric acid (UA) levels and allograft outcome. Methods We conducted a retrospective single-center analysis (N = 368) in order to assess UA blood levels post-transplant association with allograft outcome. For this study, a median serum UA level of all measured UA levels from 1 month to 1 year post renal transplantation was calculated. Results Patients were divided into 2 groups based on the median UA level measured between 1 and 12 months post-transplant. Those with median UA level ≥ 7 and ≥ 6 mg/dL (N = 164) versus median UA level < 7 and < 6 mg/dL for men and women respectively (N = 204) had lower GFR values at 1, 3 and 5 years posttransplant (mean GFR ± SD of 43.4 ± 20.6 and 58 ± 19.9 at 3 years post-transplant, p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0886-022X
1525-6049
0886022X
Relation: https://doaj.org/toc/0886-022X; https://doaj.org/toc/1525-6049
DOI: 10.1080/0886022X.2021.1969246
URL الوصول: https://doaj.org/article/aad4f8ab6d6b4dd398056cccb971db24
رقم الأكسشن: edsdoj.4f8ab6d6b4dd398056cccb971db24
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:0886022X
15256049
DOI:10.1080/0886022X.2021.1969246