دورية أكاديمية
Renal effects of uric acid: hyperuricemia and hypouricemia
| العنوان: | Renal effects of uric acid: hyperuricemia and hypouricemia |
|---|---|
| المؤلفون: | Jung Hwan Park, Yong-Il Jo, Jong-Ho Lee |
| المصدر: | The Korean Journal of Internal Medicine, Vol 35, Iss 6, Pp 1291-1304 (2020) |
| بيانات النشر: | The Korean Association of Internal Medicine, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | uric acid, hyperuricemia, hypouricemia, kidney, Medicine |
| الوصف: | The prevalence of chronic kidney disease (CKD) is increasing worldwide. Although hyperuricemia has been associated with CKD in many studies, it remains controversial whether this is the cause or the result of decreased renal function. Recent observational studies of healthy populations and patients with CKD have reported that uric acid (UA) has an independent role in the development or progression of CKD. Experimental studies have shown several potential mechanisms by which hyperuricemia may cause or promote CKD. However, other reports have indicated an association between hypouricemia and CKD. This opposing effect is hypothesized to occur because UA is a major antioxidant in human plasma and is associated with oxidative stress. In this article, we discuss the potential association between UA imbalance and CKD and how they can be treated. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1226-3303 2005-6648 |
| Relation: | http://www.kjim.org/upload/pdf/kjim-2020-410.pdf; https://doaj.org/toc/1226-3303; https://doaj.org/toc/2005-6648 |
| DOI: | 10.3904/kjim.2020.410 |
| URL الوصول: | https://doaj.org/article/50b23156da184486a1737710fc097784 |
| رقم الأكسشن: | edsdoj.50b23156da184486a1737710fc097784 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 12263303 20056648 |
|---|---|
| DOI: | 10.3904/kjim.2020.410 |