دورية أكاديمية
Optimal cutoff value of the dry eye-related quality-of-life score for diagnosing dry eye disease
| العنوان: | Optimal cutoff value of the dry eye-related quality-of-life score for diagnosing dry eye disease |
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| المؤلفون: | Xinrong Zou, Ken Nagino, Yuichi Okumura, Akie Midorikawa-Inomata, Atsuko Eguchi, Alan Yee, Keiichi Fujimoto, Maria Miura, Jaemyoung Sung, Tianxiang Huang, Kenta Fujio, Yasutsugu Akasaki, Shintaro Nakao, Hiroyuki Kobayashi, Takenori Inomata |
| المصدر: | Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024) |
| بيانات النشر: | Nature Portfolio, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Medicine, Science |
| الوصف: | Abstract This retrospective study aimed to determine the optimal cutoff values of the Dry Eye-Related Quality-of-Life Score (DEQS) questionnaire for diagnosing dry eye disease (DED) and classifying DED severities. Participants completed the DEQS questionnaire, the Japanese version of the Ocular Surface Disease Index (J-OSDI) questionnaire, and DED examinations. DED was diagnosed according to the 2016 Asia Dry Eye Society diagnostic criteria based on DED symptoms (J-OSDI ≥ 13 points) and tear film breakup time ≤ 5 s. Receiver operating characteristic (ROC) analysis was used to calculate the optimal cutoff values of the DEQS summary score for detecting DED and grading its severity. Among 427 patients, 296 (69.3%) and 131 (30.7%) were diagnosed with DED and non-DED, respectively. ROC analysis determined an optimal cutoff value of 15.0 points for DED diagnosis, with 83.5% sensitivity, 87.0% specificity, and an area under the curve of 0.915. The positive and negative predictive values for DEQS ≥ 15.0 points were 93.6% and 69.9%, respectively. DEQS cutoff values of 15.0, 20.0, and 26.8 points could be accepted for severity classification of DED subjective symptoms in clinical use and represent mild, moderate, and severe DED, respectively. Conclusively, the optimal cutoff values of DEQS enable DED detection and subjective symptom severity classification. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2045-2322 |
| Relation: | https://doaj.org/toc/2045-2322 |
| DOI: | 10.1038/s41598-024-55358-1 |
| URL الوصول: | https://doaj.org/article/50f23656cccb4e5dac7118c03f1bc2bb |
| رقم الأكسشن: | edsdoj.50f23656cccb4e5dac7118c03f1bc2bb |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 20452322 |
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| DOI: | 10.1038/s41598-024-55358-1 |