دورية أكاديمية

Characterization of Winter Dysentery Bovine Coronavirus Isolated from Cattle in Israel

التفاصيل البيبلوغرافية
العنوان: Characterization of Winter Dysentery Bovine Coronavirus Isolated from Cattle in Israel
المؤلفون: Dan David, Nick Storm, Waksman Ilan, Asaf Sol
المصدر: Viruses, Vol 13, Iss 6, p 1070 (2021)
بيانات النشر: MDPI AG, 2021.
سنة النشر: 2021
المجموعة: LCC:Microbiology
مصطلحات موضوعية: bovine coronavirus, winter dysentery, spike, S1, hemagglutinin esterase, Microbiology, QR1-502
الوصف: Bovine coronavirus (BCoV) is the causative agent of winter dysentery (WD). In adult dairy cattle, WD is characterized by hemorrhagic diarrhea and a reduction in milk production. Therefore, WD leads to significant economic losses in dairy farms. In this study, we aimed to isolate and characterize local BCoV strains. BCoV positive samples, collected during 2017–2021, were used to amplify and sequence the S1 domain of S glycoprotein and the full hemagglutinin esterase gene. Based on our molecular analysis, local strains belong to different genetic variants circulating in dairy farms in Israel. Phylogenetic analysis revealed that all local strains clustered together and in proximity to other BCoV circulating in the area. Additionally, we found that local strains are genetically distant from the reference enteric strain Mebus. To our knowledge, this is the first report providing molecular data on BCoV circulating in Israel.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 13061070
1999-4915
Relation: https://www.mdpi.com/1999-4915/13/6/1070; https://doaj.org/toc/1999-4915
DOI: 10.3390/v13061070
URL الوصول: https://doaj.org/article/50f98c759eef4d0290bd12601b35f78a
رقم الأكسشن: edsdoj.50f98c759eef4d0290bd12601b35f78a
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:13061070
19994915
DOI:10.3390/v13061070