دورية أكاديمية
Characterization of Winter Dysentery Bovine Coronavirus Isolated from Cattle in Israel
العنوان: | Characterization of Winter Dysentery Bovine Coronavirus Isolated from Cattle in Israel |
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المؤلفون: | Dan David, Nick Storm, Waksman Ilan, Asaf Sol |
المصدر: | Viruses, Vol 13, Iss 6, p 1070 (2021) |
بيانات النشر: | MDPI AG, 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Microbiology |
مصطلحات موضوعية: | bovine coronavirus, winter dysentery, spike, S1, hemagglutinin esterase, Microbiology, QR1-502 |
الوصف: | Bovine coronavirus (BCoV) is the causative agent of winter dysentery (WD). In adult dairy cattle, WD is characterized by hemorrhagic diarrhea and a reduction in milk production. Therefore, WD leads to significant economic losses in dairy farms. In this study, we aimed to isolate and characterize local BCoV strains. BCoV positive samples, collected during 2017–2021, were used to amplify and sequence the S1 domain of S glycoprotein and the full hemagglutinin esterase gene. Based on our molecular analysis, local strains belong to different genetic variants circulating in dairy farms in Israel. Phylogenetic analysis revealed that all local strains clustered together and in proximity to other BCoV circulating in the area. Additionally, we found that local strains are genetically distant from the reference enteric strain Mebus. To our knowledge, this is the first report providing molecular data on BCoV circulating in Israel. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 13061070 1999-4915 |
Relation: | https://www.mdpi.com/1999-4915/13/6/1070; https://doaj.org/toc/1999-4915 |
DOI: | 10.3390/v13061070 |
URL الوصول: | https://doaj.org/article/50f98c759eef4d0290bd12601b35f78a |
رقم الأكسشن: | edsdoj.50f98c759eef4d0290bd12601b35f78a |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 13061070 19994915 |
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DOI: | 10.3390/v13061070 |