دورية أكاديمية

Antidepressant and Anxiolytic Effects of Cod Liver Oil in Rats

التفاصيل البيبلوغرافية
العنوان: Antidepressant and Anxiolytic Effects of Cod Liver Oil in Rats
المؤلفون: Tahira Perveen*, Faiza Razi, Saida Haider, Hina Qayyum and Darakhshaan J. Haleem
المصدر: Pakistan Veterinary Journal, Vol 33, Iss 1, Pp 57-59 (2013)
بيانات النشر: University of Agriculture, Faisalabad, 2013.
سنة النشر: 2013
المجموعة: LCC:Animal culture
LCC:Veterinary medicine
مصطلحات موضوعية: Animal culture, SF1-1100, Veterinary medicine, SF600-1100
الوصف: Cod-liver oil is a rich source of omega 3 fatty acids and has been widely used as omega 3 fatty acids supplementation. Regarding omega-3 fatty acid beneficial effects in humans, this study was designed to investigate the effect of repeated administration of cod-liver oil on the locomotion and behaviors of rats, including depression, anxiety and the 5-Hydroxy tryptamine (5-HT) metabolism. After four weeks oral administration of cod-liver oil, open field test was used to measure the locomotor and exploratory activity. Elevated plus maze test was used to measure anxiety. Cod-liver oil significantly increased locomotion and produced anxiolytic effects in rats. Antidepressant effect of cod-liver oil was monitored by forced swim test (FST) in which struggling time of test animals was increased significantly. 5-HT turnover also increased significantly following the oral repeated administration of cod liver oil in test animals. The results suggest that cod-liver oil has antidepressant and anti-anxiety effects.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0253-8318
Relation: https://doaj.org/toc/0253-8318
URL الوصول: https://doaj.org/article/ad516a3d50b740438e8f1a81b99b2a32
رقم الأكسشن: edsdoj.516a3d50b740438e8f1a81b99b2a32
قاعدة البيانات: Directory of Open Access Journals