دورية أكاديمية
Antidepressant and Anxiolytic Effects of Cod Liver Oil in Rats
العنوان: | Antidepressant and Anxiolytic Effects of Cod Liver Oil in Rats |
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المؤلفون: | Tahira Perveen*, Faiza Razi, Saida Haider, Hina Qayyum and Darakhshaan J. Haleem |
المصدر: | Pakistan Veterinary Journal, Vol 33, Iss 1, Pp 57-59 (2013) |
بيانات النشر: | University of Agriculture, Faisalabad, 2013. |
سنة النشر: | 2013 |
المجموعة: | LCC:Animal culture LCC:Veterinary medicine |
مصطلحات موضوعية: | Animal culture, SF1-1100, Veterinary medicine, SF600-1100 |
الوصف: | Cod-liver oil is a rich source of omega 3 fatty acids and has been widely used as omega 3 fatty acids supplementation. Regarding omega-3 fatty acid beneficial effects in humans, this study was designed to investigate the effect of repeated administration of cod-liver oil on the locomotion and behaviors of rats, including depression, anxiety and the 5-Hydroxy tryptamine (5-HT) metabolism. After four weeks oral administration of cod-liver oil, open field test was used to measure the locomotor and exploratory activity. Elevated plus maze test was used to measure anxiety. Cod-liver oil significantly increased locomotion and produced anxiolytic effects in rats. Antidepressant effect of cod-liver oil was monitored by forced swim test (FST) in which struggling time of test animals was increased significantly. 5-HT turnover also increased significantly following the oral repeated administration of cod liver oil in test animals. The results suggest that cod-liver oil has antidepressant and anti-anxiety effects. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 0253-8318 |
Relation: | https://doaj.org/toc/0253-8318 |
URL الوصول: | https://doaj.org/article/ad516a3d50b740438e8f1a81b99b2a32 |
رقم الأكسشن: | edsdoj.516a3d50b740438e8f1a81b99b2a32 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 02538318 |
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