دورية أكاديمية
Evaluation of the VP22 gene adjuvant for enhancement of DNA vaccine against somatostatin in mice
| العنوان: | Evaluation of the VP22 gene adjuvant for enhancement of DNA vaccine against somatostatin in mice |
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| المؤلفون: | Li. Han, A.X. Liang, J. Zhang, M. Fang, G.H. Hua, L. Sang, L.Y. Geng, H.R. Wang, L.G. Yang |
| المصدر: | Animal, Vol 2, Iss 11, Pp 1569-1574 (2008) |
| بيانات النشر: | Elsevier, 2008. |
| سنة النشر: | 2008 |
| المجموعة: | LCC:Animal culture |
| مصطلحات موضوعية: | BHV-1 VP22, somatostatin, DNA vaccine, Animal culture, SF1-1100 |
| الوصف: | Somatostatin (SS) is a hormone that inhibits the secretion of growth hormone. Immunization against SS can promote the growth of animals. A novel SS-VP22 fused vaccine, pEGS2SS-V, was constructed from pEGS2SS plasmid with a VP22 gene fragment. Two times of immunization with pEGS2SS-V-induced anti-SS antibodies in mice. Compared with mice immunized with pEGS2SS and 0.85% saline, the growth performance of mice immunized with pEGS2SS-V was increased by 14.1% (P < 0.05) and 48.4% (P < 0.01) on the 2nd week after the first vaccination, respectively. The results indicated that the effects of the somatostatin DNA vaccine could be improved effectively by VP22 gene adjuvant. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1751-7311 17517311 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S175173110800284X; https://doaj.org/toc/1751-7311 |
| DOI: | 10.1017/S175173110800284X |
| URL الوصول: | https://doaj.org/article/51799d212ba44bed85ce9cd64a4bc447 |
| رقم الأكسشن: | edsdoj.51799d212ba44bed85ce9cd64a4bc447 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 17517311 |
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| DOI: | 10.1017/S175173110800284X |