ObjectiveTo investigate the epidemiological traits and potential years of life lost associated with lung cancer mortality among inhabitants of Shanghai's Pudong New Area from 1995 to 2021, in order to serve as a reference for developing intervention approaches.MethodsThe death surveillance system was used to gather statistics on lung cancer deaths. Crude mortality rate (CMR), standardized mortality rate (SMR), potential years of life lost (PYLL), average years of life lost (AYLL), annual percent change (APC) of the lung cancer deaths were analyzed. The impact of age-structural and non-age-structural factors on changes in lung cancer mortality was quantified using difference decomposition.ResultsThe CMR and SMR of lung cancer among residents in Pudong New Area between 1995 and 2021 were 58.21/105 and 26.75/105, respectively. The CMR of lung cancer increased over the years (APC=1.91%, 95%CI=1.60%‒2.30%; Z=11.487, P