دورية أكاديمية
أعرض في EDS

Serum levels of platelet endothelial cell adhesion molecule-1 (PECAM-1) and soluble vascular endothelial growth factor receptor (sVEGFR)-1 and -2 in HIV associated preeclampsia

التفاصيل البيبلوغرافية
العنوان: Serum levels of platelet endothelial cell adhesion molecule-1 (PECAM-1) and soluble vascular endothelial growth factor receptor (sVEGFR)-1 and -2 in HIV associated preeclampsia
المؤلفون: Semone Thakoordeen, Jagidesa Moodley, Thajasvarie Naicker
المصدر: Hypertension in Pregnancy, Vol 36, Iss 2, Pp 168-174 (2017)
بيانات النشر: Taylor & Francis Group, 2017.
سنة النشر: 2017
المجموعة: LCC:Gynecology and obstetrics
مصطلحات موضوعية: hiv, preeclampsia, pecam-1, svegfr-1, svegfr-2, Gynecology and obstetrics, RG1-991
الوصف: Objective: The angiogenic–antiangiogenic imbalance evident in preeclampsia (PE) may be used as a predictive tool to identify women likely to develop the clinical features in early pregnancy. Method: This retrospective study examined normotensive pregnant (n = 38) and preeclamptic (n = 38) HIV-infected and uninfected women to quantify sVEGFR-1 and -2 and PECAM-1 levels. Results: In contrast to PECAM-1, sVEGFR-1 and -2 differed according to pregnancy type (p = 0.07; p = 0.001; p = 0.002) but not by HIV status (p = 0.68; p = 0.13; p = 0.43). Conclusion: Irrespective of the HIV status, we report an upregulation of sVEGFR-1 with concomitant decline of PECAM-1 and sVEGFR-2 levels in PE compared to normotensive pregnancies.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1064-1955
1525-6065
10641955
Relation: https://doaj.org/toc/1064-1955; https://doaj.org/toc/1525-6065
DOI: 10.1080/10641955.2017.1280049
URL الوصول: https://doaj.org/article/51cb96cf3bc046fda0788d2d60499e53
رقم الأكسشن: edsdoj.51cb96cf3bc046fda0788d2d60499e53
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:10641955
15256065
DOI:10.1080/10641955.2017.1280049