دورية أكاديمية
CLINICAL AND HISTOPATHOLOGICAL CHARACTERIZATION OF LUPUS NEPHRITIS IN A TERTIARY HEALTH CENTRE, NORTH-EASTERN NIGERIA: REPORT OF FIVE CASES
| العنوان: | CLINICAL AND HISTOPATHOLOGICAL CHARACTERIZATION OF LUPUS NEPHRITIS IN A TERTIARY HEALTH CENTRE, NORTH-EASTERN NIGERIA: REPORT OF FIVE CASES |
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| المؤلفون: | Sulaiman MM, Zarami AB, Yerima A, Lawan M, Pindiga UH |
| المصدر: | Kanem Journal of Medical Sciences, Vol 15, Iss 1, Pp 73-77 (2021) |
| بيانات النشر: | Ntec Specialist, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Medicine (General) LCC:Dentistry |
| مصطلحات موضوعية: | histopathologic features, lupus nephritis, north-eastern nigeria, Medicine (General), R5-920, Dentistry, RK1-715 |
| الوصف: | Background: Lupus nephritis (LN) is an immune complex glomerulonephritis that complicates up to 40% of SLE patients. A kidney biopsy is required for diagnosis and staging of the disease. Case report: We report a cohort of five patients with LN from a tertiary health facility in northeastern Nigeria. The five patients were all women with age ranging from 26 to 55 years, and eGFR of between 6 to 154ml/minute. Four patients had normal kidney size and were biopsied whereas 1 patient had contracted kidney. Diffuse proliferative LN (Class IV) was seen in two patients while the other two patients had glomerular sclerosis (Class VI). Patients were given induction with methylprednisolone and mycophenolate mofetil (MMF). At one year follow up 2(40%) patients were in remission, 1(20%) was on maintenance hemodialysis and 2(40%) patients had died. Conclusion: Lupus nephritis is a common complication of SLE in northeastern Nigeria. Patients have features of advanced kidney disease at presentation. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2006-4772 2714-2426 |
| Relation: | https://kjmsmedicaljournal.com/wp-content/uploads/2021/07/2.Akanmu-AO-et-al-1.pdf; https://doaj.org/toc/2006-4772; https://doaj.org/toc/2714-2426 |
| DOI: | 10.36020/kjms.2021.1501.009 |
| URL الوصول: | https://doaj.org/article/52186100db09499aa242289059efbfb5 |
| رقم الأكسشن: | edsdoj.52186100db09499aa242289059efbfb5 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20064772 27142426 |
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| DOI: | 10.36020/kjms.2021.1501.009 |