دورية أكاديمية
Inflammatory Mechanism of Brucella Infection in Placental Trophoblast Cells
| العنوان: | Inflammatory Mechanism of Brucella Infection in Placental Trophoblast Cells |
|---|---|
| المؤلفون: | Yu Xiao, Mengjuan Li, Xiaoyi Guo, Hui Zeng, Xuehong Shuai, Jianhua Guo, Qingzhou Huang, Yuefeng Chu, Bo Zhou, Jake Wen, Jun Liu, Hanwei Jiao |
| المصدر: | International Journal of Molecular Sciences, Vol 23, Iss 21, p 13417 (2022) |
| بيانات النشر: | MDPI AG, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Biology (General) LCC:Chemistry |
| مصطلحات موضوعية: | Brucella, trophoblast, pathogenesis, inflammatory response, infection mechanism, Biology (General), QH301-705.5, Chemistry, QD1-999 |
| الوصف: | Brucellosis is a severe zoonotic infectious disease caused by the infection of the Brucella, which is widespread and causes considerable economic losses in underdeveloped areas. Brucella is a facultative intracellular bacteria whose main target cells for infection are macrophages, placental trophoblast cells and dendritic cells. The main clinical signs of Brucella infection in livestock are reproductive disorders and abortion. At present, the pathogenesis of placentitis or abortion caused by Brucella in livestock is not fully understood, and further research on the effect of Brucella on placental development is still necessary. This review will mainly introduce the research progress of Brucella infection of placental trophoblast cells as well as the inflammatory response caused by it, explaining the molecular regulation mechanism of Brucella leading to reproductive system disorders and abortion, and also to provide the scientific basis for revealing the pathogenesis and infection mechanism of Brucella. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1422-0067 1661-6596 |
| Relation: | https://www.mdpi.com/1422-0067/23/21/13417; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067 |
| DOI: | 10.3390/ijms232113417 |
| URL الوصول: | https://doaj.org/article/5254de5d228145ad868e6391619e29a4 |
| رقم الأكسشن: | edsdoj.5254de5d228145ad868e6391619e29a4 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14220067 16616596 |
|---|---|
| DOI: | 10.3390/ijms232113417 |