Platelets, thrombo-inflammation and cancer

التفاصيل البيبلوغرافية
العنوان:	Platelets, thrombo-inflammation and cancer
المؤلفون:	E. V. Slukhanchuk, V. O. Bitsadze, J. Kh. Khizroeva, M. V. Tretyakova, A. G. Solopova, V. N. Galkin, A. S. Shkoda, V. I. Tsibizova, V. I. Linnikov, Ismail Elalamy, J.-С. Gris, B. Brenner, A. D. Makatsariya
المصدر:	Акушерство, гинекология и репродукция, Vol 15, Iss 6, Pp 755-776 (2022)
بيانات النشر:	IRBIS LLC, 2022.
سنة النشر:	2022
المجموعة:	LCC:Gynecology and obstetrics
مصطلحات موضوعية:	platelets, thrombosis, metastasis, tumor, tumor growth, tumor progression, Gynecology and obstetrics, RG1-991
الوصف:	It has long been recognized a crucial role played by platelets in thrombosis and hemostasis. Along with that, laboratory and clinical data suggest that platelets contribute to tumor progression and metastasis through a variety of interactions with cancer cells. During oncological process, the platelet function becomes modulated via their activation and increased aggregation being one of the risk factors for developing thrombosis in cancer patients. The platelets per se enhance tumor cell dissemination, activate endothelial cells, and attract immune cells to the primary and metastatic tumor sites. In this review, we summarize the current knowledge about the complex interactions between platelets and tumor cells, as well as cells of the microenvironment, and discuss the development of new antitumor agents aimed at various arms in platelet functioning.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	Russian
تدمد:	2313-7347 2500-3194
Relation:	https://www.gynecology.su/jour/article/view/1171; https://doaj.org/toc/2313-7347; https://doaj.org/toc/2500-3194
DOI:	10.17749/2313-7347/ob.gyn.rep.2021.274
URL الوصول:	https://doaj.org/article/52a0a502d8764ed3b62c495f0c53f185
رقم الأكسشن:	edsdoj.52a0a502d8764ed3b62c495f0c53f185
قاعدة البيانات:	Directory of Open Access Journals

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الوصف
تدمد:	23137347 25003194
DOI:	10.17749/2313-7347/ob.gyn.rep.2021.274