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The metabolic effects of resumption of a high fat diet after weight loss are sex dependent in mice

التفاصيل البيبلوغرافية
العنوان: The metabolic effects of resumption of a high fat diet after weight loss are sex dependent in mice
المؤلفون: Santiago Guerra-Cantera, Laura M. Frago, María Jiménez-Hernaiz, Roberto Collado-Pérez, Sandra Canelles, Purificación Ros, Jorge García-Piqueras, Iris Pérez-Nadador, Vicente Barrios, Jesús Argente, Julie A. Chowen
المصدر: Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
بيانات النشر: Nature Portfolio, 2023.
سنة النشر: 2023
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: Abstract Dietary restriction is a frequent strategy for weight loss, but adherence is difficult and returning to poor dietary habits can result in more weight gain than that previously lost. How weight loss due to unrestricted intake of a healthy diet affects the response to resumption of poor dietary habits is less studied. Moreover, whether this response differs between the sexes and if the insulin-like growth factor (IGF) system, sex dependent and involved in metabolic control, participates is unknown. Mice received rodent chow (6% Kcal from fat) or a high-fat diet (HFD, 62% Kcal from fat) for 4 months, chow for 3 months plus 1 month of HFD, or HFD for 2 months, chow for 1 month then HFD for 1 month. Males and females gained weight on HFD and lost weight when returned to chow at different rates (p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2045-2322
Relation: https://doaj.org/toc/2045-2322
DOI: 10.1038/s41598-023-40514-w
URL الوصول: https://doaj.org/article/52e81c46d4ec4baaa7eed546d2745233
رقم الأكسشن: edsdoj.52e81c46d4ec4baaa7eed546d2745233
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20452322
DOI:10.1038/s41598-023-40514-w