دورية أكاديمية
The metabolic effects of resumption of a high fat diet after weight loss are sex dependent in mice
العنوان: | The metabolic effects of resumption of a high fat diet after weight loss are sex dependent in mice |
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المؤلفون: | Santiago Guerra-Cantera, Laura M. Frago, María Jiménez-Hernaiz, Roberto Collado-Pérez, Sandra Canelles, Purificación Ros, Jorge García-Piqueras, Iris Pérez-Nadador, Vicente Barrios, Jesús Argente, Julie A. Chowen |
المصدر: | Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023) |
بيانات النشر: | Nature Portfolio, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Medicine LCC:Science |
مصطلحات موضوعية: | Medicine, Science |
الوصف: | Abstract Dietary restriction is a frequent strategy for weight loss, but adherence is difficult and returning to poor dietary habits can result in more weight gain than that previously lost. How weight loss due to unrestricted intake of a healthy diet affects the response to resumption of poor dietary habits is less studied. Moreover, whether this response differs between the sexes and if the insulin-like growth factor (IGF) system, sex dependent and involved in metabolic control, participates is unknown. Mice received rodent chow (6% Kcal from fat) or a high-fat diet (HFD, 62% Kcal from fat) for 4 months, chow for 3 months plus 1 month of HFD, or HFD for 2 months, chow for 1 month then HFD for 1 month. Males and females gained weight on HFD and lost weight when returned to chow at different rates (p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2045-2322 |
Relation: | https://doaj.org/toc/2045-2322 |
DOI: | 10.1038/s41598-023-40514-w |
URL الوصول: | https://doaj.org/article/52e81c46d4ec4baaa7eed546d2745233 |
رقم الأكسشن: | edsdoj.52e81c46d4ec4baaa7eed546d2745233 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 20452322 |
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DOI: | 10.1038/s41598-023-40514-w |