دورية أكاديمية
The clinical value of carotid contrast-enhanced ultrasound in assessment of intraplaque neovascularization of atherosclerotic plaques
| العنوان: | The clinical value of carotid contrast-enhanced ultrasound in assessment of intraplaque neovascularization of atherosclerotic plaques |
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| المؤلفون: | Bo-wen YU, Chen WU, Zhe XUE, Wen-xin WANG, Dong-sheng KONG, Lin CHENG, Zheng-hui SUN |
| المصدر: | Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 19, Iss 3, Pp 192-198 (2019) |
| بيانات النشر: | Tianjin Huanhu Hospital, 2019. |
| سنة النشر: | 2019 |
| المجموعة: | LCC:Neurology. Diseases of the nervous system |
| مصطلحات موضوعية: | Carotid stenosis, Atherosclerosis, Neovascularization, pathologic, Ultrasonography, Neurology. Diseases of the nervous system, RC346-429 |
| الوصف: | Objective To investigate the value of predicting the vulnerability of atherosclerotic plaques in assessment of intraplaque neovascularization using carotid contrast-enhanced ultrasound. Methods A total of 24 cases diagnosed as moderate to severe carotid stenosis by digital subtraction angiography (DSA) underwent carotid endarterectomy (CEA) from September 2017 to October 2018. Preoperative carotid contrast-enhanced ultrasound and postoperative pathological examination were performed in the patients. Results Compared with postoperative pathological results, 22 cases were clearly diagnosed by preoperative carotid contrast-enhanced ultrasound, and 2 cases were missed. The precision rate of preoperative diagnosis was 91.67% (22/24). Meanwhile carotid plaques were divided into four grades (Grade Ⅰ-Ⅳ) according to the degree of enhancing extent of contrast-enhanced ultrasound. Each grade included 6 cases (25%). Pearson correlation analysis showed there was an evidently positive correlation between preoperative grade of carotid plaques and number of intraplaque CD34-positive neovessels (r = 0.871, P = 0.000). The value of area under the curve (AUC) was 0.927 (95% CI: 0.848-1.006, P = 0.000). Conclusions The grade of carotid plaques was positively related to intraplaque CD34-positive neovessels. Hence, carotid contrast-enhanced ultrasound plays an important role in predicting the vulnerability of atherosclerotic plaques and risk of ischemic stroke and judging optimal surgical time. DOI: 10.3969/j.issn.1672-6731.2019.03.009 |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Chinese |
| تدمد: | 1672-6731 |
| Relation: | http://www.cjcnn.org/index.php/cjcnn/article/view/1927; https://doaj.org/toc/1672-6731 |
| URL الوصول: | https://doaj.org/article/a5317c993e5c41468df14308a2bf1505 |
| رقم الأكسشن: | edsdoj.5317c993e5c41468df14308a2bf1505 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16726731 |
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