دورية أكاديمية
Clinical Evaluation of the Diagnostic Role of MicroRNA-155 in Breast Cancer
العنوان: | Clinical Evaluation of the Diagnostic Role of MicroRNA-155 in Breast Cancer |
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المؤلفون: | Fatemeh Hosseini Mojahed, Amir Hossein Aalami, Vahid Pouresmaeil, Amir Amirabadi, Mahdi Qasemi Rad, Amirhossein Sahebkar |
المصدر: | International Journal of Genomics, Vol 2020 (2020) |
بيانات النشر: | Wiley, 2020. |
سنة النشر: | 2020 |
المجموعة: | LCC:Genetics |
مصطلحات موضوعية: | Genetics, QH426-470 |
الوصف: | Aim. Biochemical markers, including microRNAs (miRs), may facilitate the diagnosis and prognosis of breast cancer. This study was aimed at assessing serum miR-155 expression in patients with breast cancer and receptors. Methods. This case-control study was conducted on 36 patients with breast cancer and 36 healthy individuals. After RNA extraction from the patient’s serum, cDNA was synthesized. The expression of miR-155 was measured using RT-qPCR. Demographic and histochemical data were extracted from patient documents. Data were analyzed using the Statistical Package for the Social Sciences (SPSS) software. Results. The mean age of subjects in breast cancer and control groups was 47.64±8.19 and 47.36±7.52 years, respectively. The serum miR-155 expression was higher in the cancer group (1.68±0.66) compared to the control group (p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2314-436X 2314-4378 |
Relation: | https://doaj.org/toc/2314-436X; https://doaj.org/toc/2314-4378 |
DOI: | 10.1155/2020/9514831 |
URL الوصول: | https://doaj.org/article/532c252e06d5451a8324f7fc0bdd79ca |
رقم الأكسشن: | edsdoj.532c252e06d5451a8324f7fc0bdd79ca |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 2314436X 23144378 |
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DOI: | 10.1155/2020/9514831 |