دورية أكاديمية
Alterações estruturais dos vasos pulmonares e artérias coronárias na síndrome do coração esquerdo hipoplásico.
العنوان: | Alterações estruturais dos vasos pulmonares e artérias coronárias na síndrome do coração esquerdo hipoplásico. |
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المؤلفون: | A Macedo, E Pinto, S Ramos, M J Brito, M M Costa, I Serrano, I Torrezão, M Lima, M E Silva, M L Roriz |
المصدر: | Acta Médica Portuguesa, Vol 4, Iss 5 (1991) |
بيانات النشر: | Ordem dos Médicos, 1991. |
سنة النشر: | 1991 |
المجموعة: | LCC:Medicine LCC:Medicine (General) |
مصطلحات موضوعية: | Medicine, Medicine (General), R5-920 |
الوصف: | In order to correlate gross morphological features with pulmonary and coronary vasculature changes in hypoplastic left heart syndrome (HLHS) 15 heart-lung necropsy specimens from neonates were analysed. Histology of left atrium wall, lung vessels with pulmonary arteriolar disease morphometric grading, study of intra and extra pulmonary wall veins and coronary arteries were recorded. Classic HLHS was observed in 11, and DORV with mitral atresia in 4, the foramen ovale (FO) being the only left atrium outflow tract in all. All specimens had increased % of thickness and muscular extension of arterioles and increased wall thickness of pulmonary veins, but severer arteriolar and venous changes with left atrium fibrosis were noticed in 8 specimens with either closed FO (3 cases) or mean FO diameter (d) of 5 mm when compared with specimens with mean FOd of 9 mm. Coronary arteries histology disclosed in 4 of 8 specimens with opened but hypoplastic mitral valve, intima proliferative changes with lumen narrowing, not observed in 7 specimens with mitral valve atresia. We concluded that in HLHS closed or restrictive FO and permeable mitral valve may predispose neonates to respiratory complications, right ventricle abnormal function and arrhythmias, specially after cardiac surgery. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English Portuguese |
تدمد: | 0870-399X 1646-0758 |
Relation: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3367; https://doaj.org/toc/0870-399X; https://doaj.org/toc/1646-0758 |
DOI: | 10.20344/amp.3367 |
URL الوصول: | https://doaj.org/article/a53470635f8045cebac9c4db615714e2 |
رقم الأكسشن: | edsdoj.53470635f8045cebac9c4db615714e2 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 0870399X 16460758 |
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DOI: | 10.20344/amp.3367 |