دورية أكاديمية

RNA-based pharmacotherapy for tumors: From bench to clinic and back

التفاصيل البيبلوغرافية
العنوان: RNA-based pharmacotherapy for tumors: From bench to clinic and back
المؤلفون: Xiangping Liang, Dongpei Li, Shuilong Leng, Xiao Zhu
المصدر: Biomedicine & Pharmacotherapy, Vol 125, Iss , Pp 109997- (2020)
بيانات النشر: Elsevier, 2020.
سنة النشر: 2020
المجموعة: LCC:Therapeutics. Pharmacology
مصطلحات موضوعية: RNA therapy, RNA drugs, Cancer immunotherapy, Clinical trials, Therapeutics. Pharmacology, RM1-950
الوصف: RNA therapy is a treatment that regulates cell proteins and cures diseases by affecting the metabolism of mRNAs in cells, which has cut a figure in the studies on various incurable illnesses like hereditary diseases, tumors, etc. In this review, we introduced the discovery and development of RNA therapy and discussed its classification, mechanisms, advantages, and challenges. Moreover, we highlighted how RNA therapy works in killing tumor cells as well as what progresses it has made in related researches. And the development of RNA anti-tumor drugs and the clinical trial process were also included.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0753-3322
Relation: http://www.sciencedirect.com/science/article/pii/S0753332220301888; https://doaj.org/toc/0753-3322
DOI: 10.1016/j.biopha.2020.109997
URL الوصول: https://doaj.org/article/536362a53ee442a7a0341cb07a2d920c
رقم الأكسشن: edsdoj.536362a53ee442a7a0341cb07a2d920c
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:07533322
DOI:10.1016/j.biopha.2020.109997