دورية أكاديمية
The Effects of Topical Agent (Kelo-Cote or Contractubex) Massage on the Thickness of Post-Burn Scar Tissue Formed in Rats
| العنوان: | The Effects of Topical Agent (Kelo-Cote or Contractubex) Massage on the Thickness of Post-Burn Scar Tissue Formed in Rats |
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| المؤلفون: | Won Jin Ko, Young Cheon Na, Bum Sin Suh, Hyeon A Kim, Woo Hoe Heo, Gum Ha Choi, Seo Ul Lee |
| المصدر: | Archives of Plastic Surgery, Vol 40, Iss 06, Pp 697-704 (2013) |
| بيانات النشر: | Thieme Medical Publishers, Inc., 2013. |
| سنة النشر: | 2013 |
| المجموعة: | LCC:Surgery |
| مصطلحات موضوعية: | burns, cicatrix, hypertrophic, wound healing, massage, Surgery, RD1-811 |
| الوصف: | Background We conducted an experimental study to compare the effect of massage using topical agents (Kelo-cote or Contractubex) on scar formation by massaging the healed burn wound on the dorsal area of Sprague-Dawley (SD) rats. Methods Four areas of second degree contact burn were made on the dorsal area of each of 15 SD rats, using a soldering iron 15 mm in diameter. After gross epithelialization in the defect, 15 SD rats were randomly divided into four groups: the Kelo-cote group, Contractubex group, Vaseline group, and control group. Rats in three of the groups (all but the Control group) were massaged twice per day for 5 minutes each day, while those in the Control group were left unattended. For histologic analysis, we performed a biopsy and evaluated the thickness of scar tissue. Results In the Kelo-cote and Contractubex groups, scar tissue thicknesses showed a significant decrease, compared with the Vaseline and control groups. However, no significant differences were observed between the Kelo-cote and Contractubex groups. In the Vaseline group, scar tissue thicknesses showed a significant decrease, compared with the control groups. Conclusions The findings of this study suggest that massage using a topical agent is helpful in the prevention of scar formation and that massage only with lubricant (no use of a topical agent) also has a considerable effect, although not as much as the use of a topical agent. Thus, we recommend massage with a topical agent on the post-burn scar as an effective method for decreasing the scar thickness. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2234-6163 2234-6171 |
| Relation: | https://doaj.org/toc/2234-6163; https://doaj.org/toc/2234-6171 |
| DOI: | 10.5999/aps.2013.40.6.697 |
| URL الوصول: | https://doaj.org/article/53658d20ec3448ad9c53d7dbbdc4a785 |
| رقم الأكسشن: | edsdoj.53658d20ec3448ad9c53d7dbbdc4a785 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22346163 22346171 |
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| DOI: | 10.5999/aps.2013.40.6.697 |