دورية أكاديمية
Nomogram to diagnosis of obstructive sleep apnoea‐hypopnoea syndrome in high‐risk Chinese adult patients
| العنوان: | Nomogram to diagnosis of obstructive sleep apnoea‐hypopnoea syndrome in high‐risk Chinese adult patients |
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| المؤلفون: | Jie Liu, Feng Pang, Xiaofeng Huang, Xiangmin Zhang, Minmin Lin, Wenmin Deng, Tianrun Liu, Zhen Long |
| المصدر: | The Clinical Respiratory Journal, Vol 17, Iss 9, Pp 931-940 (2023) |
| بيانات النشر: | Wiley, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Diseases of the respiratory system |
| مصطلحات موضوعية: | cross‐sectional studies, nomograms, obstructive, sleep apnoea, sleep apnoea syndromes, Diseases of the respiratory system, RC705-779 |
| الوصف: | Abstract Introduction Many scales are designed to screen for obstructive sleep apnoea‐hypopnoea syndrome (OSAHS); however, there is a lack of an efficiently and easily diagnostic tool, especially for Chinese. Therefore, we conduct a cross‐sectional study in China to develop and validate an efficient and simple clinical diagnostic model to help screen patients at risk of OSAHS. Methods This study based on 782 high‐risk patients (aged >18 years) admitted to the Sleep Medicine department of the Sixth Affiliated Hospital, Sun Yat‐sen University from 2015 to 2021. Totally 34 potential predictors were evaluated. We divided all patients into training and validation dataset to develop diagnostic model. The univariable and multivariable logistic regression model were used to build model and nomogram was finally built. Results Among 602 high‐risk patients with median age of 46 (37, 56) years, 23.26% were women. After selecting using the univariate logistic model, 15 factors were identified. We further used the stepwise method to build the final model with five factors: age, BMI, total bilirubin levels, high Berlin score, and symptom of morning dry mouth or mouth breathing. The AUC was 0.780 (0.711, 0.848), with sensitivity of 0.848 (0.811, 0.885), specificity of 0.629 (0.509, 0.749), accuracy of 0.816 (0.779, 0.853). The discrimination ability had been verified in the validation dataset. Finally, we established a nomogram model base on the above final model. Conclusion We developed and validated a predictive model with five easily acquire factors to diagnose OSAHS patient in high‐risk population with well discriminant ability. Accordingly, we finally build the nomogram model. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1752-699X 1752-6981 |
| Relation: | https://doaj.org/toc/1752-6981; https://doaj.org/toc/1752-699X |
| DOI: | 10.1111/crj.13682 |
| URL الوصول: | https://doaj.org/article/5372d31f5702400fb05315f552c27457 |
| رقم الأكسشن: | edsdoj.5372d31f5702400fb05315f552c27457 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 1752699X 17526981 |
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| DOI: | 10.1111/crj.13682 |