دورية أكاديمية
Role of sulfiredoxin in systemic diseases influenced by oxidative stress
| العنوان: | Role of sulfiredoxin in systemic diseases influenced by oxidative stress |
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| المؤلفون: | Asha Ramesh, Sheeja S. Varghese, Jayakumar Doraiswamy, Sankari Malaiappan |
| المصدر: | Redox Biology, Vol 2, Iss C, Pp 1023-1028 (2014) |
| بيانات النشر: | Elsevier, 2014. |
| سنة النشر: | 2014 |
| المجموعة: | LCC:Medicine (General) LCC:Biology (General) |
| مصطلحات موضوعية: | Sulfiredoxin, Antioxidant, Oxidative stress, Reactive oxygen species, Systemic diseases, Medicine (General), R5-920, Biology (General), QH301-705.5 |
| الوصف: | Sulfiredoxin is a recently discovered member of the oxidoreductases family which plays a crucial role in thiol homoeostasis when under oxidative stress. A myriad of systemic disorders have oxidative stress and reactive oxygen species as the key components in their etiopathogenesis. Recent studies have evaluated the role of this enzyme in oxidative stress mediated diseases such as atherosclerosis, chronic obstructive pulmonary disease and a wide array of carcinomas. Its action is responsible for the normal functioning of cells under oxidative stress and the promotion of cell survival in cancerous cells. This review will highlight the cumulative effects of sulfiredoxin in various systemic disorders with a strong emphasis on its target activity and the factors influencing its expression in such conditions. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2213-2317 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2213231714001013; https://doaj.org/toc/2213-2317 |
| DOI: | 10.1016/j.redox.2014.09.002 |
| URL الوصول: | https://doaj.org/article/5410f529096847569a070e44805eda42 |
| رقم الأكسشن: | edsdoj.5410f529096847569a070e44805eda42 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22132317 |
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| DOI: | 10.1016/j.redox.2014.09.002 |